Gum fluid study seeks clues to implant disease
NCT ID NCT07379892
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 54 people with peri-implantitis, an infection around dental implants. Researchers measured three substances (TREM-1, MMP-8, and TIMP-1) in the fluid around the implants. The goal was to see if these markers could help understand or diagnose the condition better.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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54 people
The number who actually took part.
- Started
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Jun 2023
- Finished
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May 2024
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
All patients had at least one implant, and this implant had been in place for at least one year since the implant-supported prosthesis was made.
- Ages
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18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Systemically healthy * Pregnancy or lactation Exclusion Criteria: * osteoporosis * rheumatoid arthritis * autoimmune disease * diabetes
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
Aydın Adnan Menderes University
Aydin, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a bone graft rescue failing dental implants?
- Can a Cow-Bone graft save failing dental implants?
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- A deep-dive into gum disease: can a standard cleaning calm the body's tissue-damage signals?
- Could tiny metal shavings from dental implants fuel gum disease?