New powder may better clean dental implants and protect surfaces
NCT ID NCT07140146
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests if a trehalose powder cleans dental implants better than a standard glycine powder in people with gum inflammation around implants (peri-implant mucositis). Forty adults will receive non-surgical cleaning with one of the powders and be checked at 1, 3, and 6 months. The goal is to see which powder reduces plaque and inflammation more while keeping the implant surface intact.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 40 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Aug 2025
- Expected to finish
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Jun 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 70 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged between 18 and 70 years * Presence of peri-implant mucositis, defined as bleeding on probing (BoP) around implants without radiographic evidence of bone loss beyond initial remodeling * Visible biofilm on implant surfaces * Ability to understand and sign informed consent * Good oral hygiene and patient compliance * Availability for all follow-up visits (1, 3, and 6 months) Exclusion Criteria: * Presence of systemic conditions that may affect healing (e.g., uncontrolled diabetes, immunosuppression) * Current smokers or former smokers who quit less than 6 months ago * Pregnant or breastfeeding women * Use of antibiotics or anti-inflammatory drugs in the 3 months prior to baseline * Presence of peri-implantitis (i.e., bleeding on probing with concomitant radiographic bone loss) * History of head and neck radiotherapy * Presence of pacemakers or cardiac stimulators * Neurological or psychological disorders affecting study compliance
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Unit of Orthodontics and Pediatric Dentistry - Section of Dentistry - Department of Clinical, Surgical, Diagnostic and Pediatrics - University of Pavia
RECRUITINGPavia, Lombardy, 27100, Italy
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Other studies related to the condition(s) this trial covers.
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