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Can a phone app ease the emotional toll of glaucoma?

NCT ID NCT06053307

Symptom relief Sponsor: Duke University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a mobile app that teaches Acceptance and Commitment Therapy (ACT) to help people with glaucoma cope with anxiety, depression, and emotional distress. Researchers worked with 28 patients to see if the app was acceptable and easy to use. The goal was to lay the groundwork for a larger future study on whether this approach can improve emotional well-being and quality of life.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Acceptance and Commitment Therapy (ACT) delivered via a mobile app
What this could lead to
If it works, this could offer a practical way to help glaucoma patients cope with emotional distress and improve their quality of life.
What could go wrong
This is a very small pilot study with only 28 participants and no control group, so results may not apply broadly. The intervention is behavioral and may not work for everyone.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

28 people

The number who actually took part.

Started

Apr 2025

Finished

Jan 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria * diagnosed with mild, moderate, or severe chronic glaucoma (e.g., POAG), * had a visual field within the past year at the main Duke Eye Center, * been prescribed pressure lowering eye drop medication, * at least mild distress (based on PHQ-4), * 18 years old, * able to understand, speak, and read English, and * be able to provide informed consent. Exclusion Criteria * diagnosed with borderline glaucoma or as a glaucoma suspect, * had a glaucoma surgery in past month (e.g., trabeculectomy, glaucoma drainage device/tube), * visual acuity of worse than 20/70 in the better seeing eye, * diagnosed with a major medical conditions (e.g., cancer, or another visual disorder, like macular degeneration), * diagnosed with a psychiatric conditions (e.g., schizophrenia, bipolar disorder), and * reported or suspected cognitive impairment indicated by provider or chart review.

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Conditions

The condition(s) this trial relates to.

anxiety anxiety disorder Depression depressive disorder open-angle glaucoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Anxiety Depression Distress, emotional Glaucoma, primary open angle

Contacts and locations

Locations

  • Duke University Eye Center

    Durham, North Carolina, 27705, United States

More trials for these conditions

Other studies related to the condition(s) this trial covers.