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New hope for immunotherapy side effects: which drug works best for colitis?

NCT ID NCT04407247

First seen Jan 05, 2026 · Last updated Jun 17, 2026 · Updated 27 times

Summary

This study compares two medications, infliximab and vedolizumab, to treat colitis (colon inflammation) caused by immune checkpoint inhibitor therapy in cancer patients. About 47 adults with genitourinary cancer, melanoma, or non-small cell lung cancer are participating. The goal is to see which drug works better to control this side effect and help patients recover.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • M D Anderson Cancer Center

    Houston, Texas, 77030, United States

Conditions

The condition(s) this trial relates to.

cancer colitis male reproductive organ cancer malignant urinary system neoplasm melanoma non-small cell lung carcinoma Urogenital Neoplasms

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.