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New combo may help women with early breast cancer avoid mastectomy

NCT ID NCT06843681

First seen Jan 04, 2026 · Last updated Apr 28, 2026 · Updated 21 times

Summary

This study tests whether giving two drugs (trastuzumab and a taxane) before surgery can shrink HER2-positive breast cancer that hasn't spread, allowing more women to have breast-conserving surgery instead of mastectomy. About 54 women aged 18-70 with tumors at least 2 cm will receive 4-6 cycles of treatment. The main goal is to see how many can then have breast-conserving surgery.

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Contacts and locations

Locations

  • Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University

    Guangzhou, Guangdong, China

Conditions

Explore the condition pages connected to this study.