New combo therapy may help women with early breast cancer avoid mastectomy
NCT ID NCT06843681
First seen Jan 04, 2026 · Last updated Jun 11, 2026 · Updated 29 times
Summary
This study tests whether giving two drugs (trastuzumab and a taxane) before surgery can shrink HER2-positive breast carcinoma in situ tumors enough to allow breast-conserving surgery instead of mastectomy. About 54 women aged 18-70 with tumors at least 2 cm will receive 4-6 cycles of treatment. The main goal is to see how many can have breast-conserving surgery after therapy.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Guangzhou, Guangdong, China
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
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