Capsaicin cream vs. diclofenac gel: which eases TMJ pain better?
NCT ID NCT07598994
First seen May 26, 2026 · Last updated Jun 21, 2026 · Updated 5 times
Summary
This completed trial tested whether capsaicin cream (made from chili peppers) or diclofenac gel (a common anti-inflammatory) works better for chronic jaw joint pain. Fifty women applied the cream or gel four times daily for a week. Researchers measured pain, jaw function, and pressure sensitivity at one week and one month.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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Istanbul University Faculty of Dentistry
Istanbul, Istanbul, 34093, Turkey (Türkiye)
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
capsaicin cream (0.075%) and diclofenac gel (1%)
What this could lead to
If capsaicin works better, it could offer a new, non-drug option for managing chronic jaw pain.
What could go wrong
This is a small, single-blind trial with only 50 women, so results may not apply to everyone. Capsaicin can cause burning or irritation.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.