Whitening toothpaste shows promise in stain removal study
NCT ID NCT07428603
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a whitening toothpaste against a regular toothpaste to see if it could remove surface stains from teeth. 118 adults brushed twice daily for six weeks. Researchers measured stain levels at the start and after 7, 14, 28, and 42 days. The goal was to see if the whitening toothpaste worked better than the control.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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118 people
The number who actually took part.
- Started
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Aug 2024
- Finished
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Sep 2024
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults 18-65 years in good general health * Mean MLSI score ≥1.5 on labial surfaces of at least 8 of 12 anterior teeth * Adequate oral hygiene and willingness to comply with study requirements * Dental prophylaxis within past 18 months but not within past 3 months * Willing to refrain from other whitening or oral care products during the study Exclusion Criteria: * Significant medical conditions or oral pathology affecting assessments * History of adverse reactions to oral hygiene products * Orthodontic appliances or restorations interfering with stain assessment * Moderate or advanced periodontitis * Recent bleaching or whitening treatments * Pregnant or nursing
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Salus Research, Inc.
Fort Wayne, Indiana, 46825, United States