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Whitening toothpaste shows promise in stain removal study

NCT ID NCT07428603

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a whitening toothpaste against a regular toothpaste to see if it could remove surface stains from teeth. 118 adults brushed twice daily for six weeks. Researchers measured stain levels at the start and after 7, 14, 28, and 42 days. The goal was to see if the whitening toothpaste worked better than the control.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

118 people

The number who actually took part.

Started

Aug 2024

Finished

Sep 2024

Lead sponsor

A company

The lead sponsor is a pharmaceutical, biotech, or medical-device company.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Adults 18-65 years in good general health * Mean MLSI score ≥1.5 on labial surfaces of at least 8 of 12 anterior teeth * Adequate oral hygiene and willingness to comply with study requirements * Dental prophylaxis within past 18 months but not within past 3 months * Willing to refrain from other whitening or oral care products during the study Exclusion Criteria: * Significant medical conditions or oral pathology affecting assessments * History of adverse reactions to oral hygiene products * Orthodontic appliances or restorations interfering with stain assessment * Moderate or advanced periodontitis * Recent bleaching or whitening treatments * Pregnant or nursing

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Salus Research, Inc.

    Fort Wayne, Indiana, 46825, United States