New gel may soothe sensitive teeth in just 14 days
NCT ID NCT07596797
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a special tooth gel can help adults with sensitive teeth. Thirty-one participants used the gel three times a day for two weeks. Researchers measured pain from cold air and touch before and after treatment to see if sensitivity improved.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- desensitizing tooth gel
- What this could lead to
- If it works, this could provide a simple, at-home option to reduce tooth pain from sensitivity.
- What could go wrong
- This is a small, completed study with only 31 participants and no comparison group, so results may not apply to everyone. The gel may not work for all types of sensitivity.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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31 people
The number who actually took part.
- Started
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Jul 2024
- Finished
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Jul 2024
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 65 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Healthy female and male subjects (no specific repartition) * Aged between 18 years old * Subjects with dentine hyperesthesia * Have a minimum of two hypersensitive teeth anterior to non-consecutive molars, with cervical erosion/abrasion or gingival recession, and with a grade greater than or equal to 1 on the verbal rating scale (VRS) after tactile simulation, and greater than or equal to 1 on the Schiff cold air sensitive scale at the beginning of the study. * Subjects certifying the truthfulness of the personal data disclosed to the investigator * Subjects able to understand the language used in the investigation canter and the information given by the investigator * Subjects able to respect the instructions given by the investigator as well as able to respect the study constraints and specific requirements * The pharmacological therapy (except for the pharmacological therapy in the non-inclusion criteria) should be stable for at least one month without any changes expected or planned during the study * Commitment not to change the daily routine or the lifestyle * Subjects who have not been recently involved in any other similar study * Commitment not to use during the study period other products with the same effect of the tested product * Subjects informed about the test procedures and who have signed a consent form. Exclusion Criteria: * Subjects participating or planning to participate in other clinical trials; * Subjects deprived of liberty by administrative or judicial decision or under guardianship; * Subjects who cannot be contacted in an emergency; * Subjects admitted to a health or social center; * Subjects planning hospitalization during the study; * Subjects who participated in a similar study without respecting an adequate washout period (used any desensitizing agents during the last three months); * Subjects who have used anti sensitivity products in the 4 weeks prior to screening; * Subjects under pharmacological treatments that the investigator considers incompatible with the requirements of the study; * Subjects who have had active caries within 12 months or who are at risk of caries development (multiple dental restorations, crowns with compromised margin) per examiners discretion; * Subjects who have shown allergies or sensitivity to any component of the product; * Subject breastfeeding, pregnant or not willing to take the necessary precautions to avoid pregnancy during the study (for women of childbearing age). * Any tooth surface adjacent to those surfaces under investigation, which in the opinion of the investigator have any other condition that provides symptoms confusing with those of cervical dentin hypersensitivity.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CLINICA CIURANA Centre Dental
Barcelona, Spain