Magnetic pulses timed to brain rhythms may quiet tremors without surgery
NCT ID NCT07574164
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tests whether transcranial magnetic stimulation (TMS) timed to a person's own tremor cycle can reduce shaking in Essential Tremor and Parkinson's disease. Twenty participants with each condition will receive TMS pulses over the motor cortex while their tremor is recorded. The goal is to see if this non-invasive approach can suppress tremor better than no stimulation, potentially offering a new option for people who cannot tolerate medications or want to avoid surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Transcranial magnetic stimulation (TMS) device
- What this could lead to
- If it works, this could point toward a non-invasive, drug-free way to reduce tremor in Essential Tremor and Parkinson's disease.
- What could go wrong
- This is a very early, small study (20 participants per group) testing only short-term effects. The tremor reduction may be small or not last, and the approach may not work for everyone.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 20 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Jan 2024
- Expected to finish
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Jan 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * having either essential tremor or Parkinson's disease Exclusion Criteria: * contraindications to brain stimulation
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Oxford Center for Integrative Neuroimaging
RECRUITINGOxford, Oxfordshire, OX3 9DU, United Kingdom
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Sharper brain scans could reveal Parkinson's changes sooner
- Leg cuffs plus walking: a new way to steady Parkinson's balance?
- Reading the Brain's signals to predict who benefits from deep brain stimulation
- Walking memory tests may reveal early Parkinson's clues
- Hair-Thin electrodes tested to Fine-Tune brain stimulation
- Brain training through implanted electrodes aims to quiet Parkinson's tremors