Could a magnetic helmet calm Seizure-Like brain waves in sleeping children?
NCT ID NCT04034030
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study tested a wearable device that uses magnetic pulses to stimulate the brain in 10 children with a rare epilepsy called CSWS, where abnormal brain activity occurs during sleep. The device was applied for just 10 minutes to the area causing the seizures. Researchers measured changes in brain wave patterns on EEG to see if the treatment reduced abnormal activity.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Transcranial Magnetic Stimulation (TMS) device
- What this could lead to
- If it works, this could offer a non-drug way to reduce abnormal brain activity during sleep in children with CSWS.
- What could go wrong
- This is a very small, early study with only 10 children. The treatment is given just once for 10 minutes, so any effect may be short-lived. It may not work at all.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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10 people
The number who actually took part.
- Started
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Aug 2019
- Finished
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May 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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3 to 21 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Patients between the ages of 3 and 21 years old, * An electroclinical diagnosis of focal CSWS as defined by ILAE * SWI of ≥ 85% in sleep on EEG's performed on previous or most recent EEG study. * No change in antiepileptic drugs (AED) in last 2 week, or patients not on any AED Exclusion Criteria: * Presence of metal implants or metallic devices in the head * Any history of drug or alcohol abuse * Presence of cardiac pacemaker * Generalized CSWS All study patients will be enrolled for treatment with TMS to see if this modality of treatment has any effect on SWI on CSWS. Additional exclusions are: * Adults unable to consent * Pregnant women * Prisoners * Wards of the state * Non English speaking subjects and families
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Children's Mercy Hospital
Overland Park, Kansas, 66211, United States
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Other studies related to the condition(s) this trial covers.