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Brain zaps may alter emotional perception, study hints

NCT ID NCT07191275

Knowledge-focused Sponsor: Prof. Dominique de Quervain, MD Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a non-invasive brain stimulation technique called TMS can change how people perceive and remember emotional pictures. 33 healthy adults will receive TMS over specific brain areas and then rate emotional images. The goal is to understand how TMS affects emotional processing, which could inform future treatments for mental health conditions.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcranial magnetic stimulation (TMS)
What this could lead to
If it works, this could point toward a non-invasive way to influence emotional memory, potentially helping with conditions like PTSD or anxiety.
What could go wrong
This is a small, early-phase study in healthy volunteers, so results may not apply to patients. TMS is generally safe but can cause mild discomfort or headache.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 33 people

The number the study aims to enrol. It can still change while the study runs.

Started

Nov 2025

Expected to finish

Oct 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 30 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Generally healthy * Normotensive (BP 90/60mmHg - 140/90mmHg) * BMI: 18 - 30 kg/m2 * Fluent in speaking German Exclusion Criteria: * Metal in the head area (e.g., splinters, fragments, clips, etc.) * Implanted neurostimulator (e.g., DBS, epidural/subdural, VNS) * Cardiac pacemaker or intracardiac lines * Medication infusion device * Non removable metal piercings in the head area, pivot teeth (retainers are no exclusion criterion) * Tattoos (head area) less than 3 months old or older than 20 years * Condition after neurosurgery * Hearing problems or tinnitus * Not able to sit still due to tremor, tics, itching * History of repeated syncope * Head trauma diagnosed as concussion or associated with loss of consciousness * diagnosis of epilepsy, or a convulsion or a seizure in the past of the participant or his/her close family (parents and siblings) * TMS in the past showing problems * Spinal or ventricular derivations * Positive pregnancy test * Alcohol intake 12 hours before TMS visits * Regular intake of any medication (excluding oral contraceptives) * CNS-active medication or illegal drugs 48h before TMS visits * Individual's rMT above the limits of rTMS device * Suicidal tendency as measured by Montgomery-Åsberg Depression Rating Scale (MADRS), item 10 \> 0

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Emotional memory

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University of Basel, Division of Cognitive Neuroscience

    RECRUITING

    Basel, Canton of Basel-City, 4055, Switzerland

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