New radiation-chemo combo aims to boost stem cell transplant success in high-risk leukemia
NCT ID NCT03494569
First seen Nov 10, 2025 · Last updated Jun 17, 2026 · Updated 30 times
Summary
This early-stage study tests the safety and best dose of a targeted radiation therapy (TMLI) combined with two chemotherapy drugs before a donor stem cell transplant. It includes 36 people with high-risk acute leukemia or myelodysplastic syndrome (MDS). The goal is to prepare the body for transplant by destroying cancer cells and making room for healthy donor stem cells.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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City of Hope Medical Center
Duarte, California, 91010, United States
Conditions
The condition(s) this trial relates to.
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