New study tests if switching anesthesia Mid-Surgery can prevent Post-Op sickness
NCT ID NCT07270289
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study will compare two anesthesia methods—total intravenous anesthesia (TIVA) and inhalational anesthesia—to see which better prevents nausea and vomiting after laparoscopic obstetric surgery. About 98 women aged 18-50 undergoing elective laparoscopic procedures will be randomly assigned to one of the two techniques. The goal is to find a simple way to improve comfort and recovery after surgery.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- propofol-based total intravenous anesthesia (TIVA) and inhalational anesthesia (sevoflurane/desflurane)
- What this could lead to
- If TIVA works better, it could offer a simple way to reduce nausea and vomiting after laparoscopic obstetric surgery, improving patient comfort and recovery.
- What could go wrong
- This is a small, early-stage trial (98 participants) that has not yet started. Results may not apply to all patients, and individual responses to anesthesia vary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 98 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Dec 2025
An estimate. Start dates often move.
- Expected to finish
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Dec 2027
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 50 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Female, age 18-50 years. * Elective laparoscopic procedure under general anaesthesia with endotracheal intubation. * Expected surgical duration ≥ 30 minutes. -.Ability to consent and complete questionnaires Exclusion Criteria: * Pregnancy or lactation. * BMI ≥ 40 kg/m²; severe cardiopulmonary disease; hepatic/renal failure. * History of malignant hyperthermia or contraindication to study drugs. * Known allergy to propofol, , , sevoflurane/desflurane.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The official record
The full official record for this study. This one lists no contact details, but it is the first place any would appear.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.