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Glue instead of stitches for mouth biopsies? small trial tests faster healing

NCT ID NCT07654166

Symptom relief Sponsor: Damascus University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a special medical glue (tissue adhesive) can replace traditional stitches for closing wounds inside the mouth after a biopsy. Twenty-eight people with small mouth growths will be randomly assigned to get either the glue or stitches. Researchers will measure how well the wound heals, how long the procedure takes, and how much pain patients feel afterward.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
PeriAcryl 90 HV (tissue adhesive)
What this could lead to
If it works, this could offer a faster, less painful alternative to stitches for closing mouth wounds after biopsies.
What could go wrong
This is a very small early trial with only 28 people, so results may not apply to everyone. The adhesive might not hold as well as stitches in all cases.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 28 people

The number the study aims to enrol. It can still change while the study runs.

Started

Aug 2025

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 80 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: -Patients clinically diagnosed with oral fibroma located on the labial mucosa (lip) or buccal mucosa (cheek). * Lesion requires excisional biopsy. * Lesion size greater than 3 mm and less than 3 cm in greatest diameter. Exclusion Criteria: * Pregnant or breastfeeding women. * Patients taking anticoagulant medications (blood thinners). * Patients with infectious diseases such as hepatitis, HIV, etc. * Patients taking immunosuppressants. * Patients with uncontrolled diabetes mellitus. * Patients taking medications that affect bleeding and wound healing.

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Conditions

The condition(s) this trial relates to.

Mouth Neoplasms oral cavity neoplasm oral fibroma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Mouth neoplasms

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Damascus University ,Department of Oral Medicine, Faculty of Dentistry

    RECRUITING

    Damascus, Mazzh, Syria

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