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Experimental drug offers hope for rare brain development disorder in toddlers

NCT ID NCT02396459

Summary

This study is testing whether a drug called tiratricol can help young boys with a rare genetic disorder called Allan-Herndon-Dudley Syndrome. The condition causes severe brain development problems and harmful overactivity in other body systems. Boys aged 30 months or younger will take the drug for nearly two years to see if it improves their movement skills and brain development while reducing harmful effects on the body.

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Contacts and locations

Locations

  • Charité - Universitätsmedizin Berlin Institut fur experimental paediatrische endokrinologie

    Berlin, 13353, Germany

  • Charles University and Motol University Hospital; The department of peadiatrics of the 2nd faculty of medicine

    Prague, 15006, Czechia

  • Children's Hospital of Philadelphia

    Philadelphia, Pennsylvania, 19104, United States

  • Erasmus MC

    Rotterdam, 3015 GD, Netherlands

  • Oregon Health & Science University (OHSU) Doernbecher Childrens Hospital

    Portland, Oregon, 97239, United States

Conditions

Explore the condition pages connected to this study.