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Kidney shield after bypass? drug trial halted early

NCT ID NCT05524051

First seen Nov 19, 2025 · Last updated May 21, 2026 · Updated 28 times

Summary

This study tested a drug called TIN816 to see if it could prevent acute kidney injury in adults after heart surgery. About 102 people were planned to take part, but the study was stopped early. The goal was to measure kidney function using a blood test called serum creatinine.

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Contacts and locations

Locations

  • Duke Univ Medical Center

    Durham, North Carolina, 27710, United States

  • Mayo Clinic Phoenix

    Phoenix, Arizona, 85054, United States

  • Novartis Investigative Site

    CABA, Buenos Aires, C1118AAT, Argentina

  • Novartis Investigative Site

    Buenos Aires, C1428DCO, Argentina

  • Novartis Investigative Site

    CABA, C1181ACH, Argentina

  • Novartis Investigative Site

    Genk, Limburg, 3600, Belgium

  • Novartis Investigative Site

    Leuven, 3000, Belgium

  • Novartis Investigative Site

    Salvador, Estado de Bahia, 40323-010, Brazil

  • Novartis Investigative Site

    São Paulo, São Paulo, 05403 000, Brazil

  • Novartis Investigative Site

    Montreal, Quebec, H1T 1C8, Canada

  • Novartis Investigative Site

    Montreal, Quebec, H2X 0A9, Canada

  • Novartis Investigative Site

    Montreal, Quebec, H4J 1C5, Canada

  • Novartis Investigative Site

    Québec, Quebec, GIV 4G5, Canada

  • Novartis Investigative Site

    Ostrava, Poruba, 708 52, Czechia

  • Novartis Investigative Site

    Tartu, 50406, Estonia

  • Novartis Investigative Site

    Nantes, 44093, France

  • Novartis Investigative Site

    Neuilly-sur-Seine, 92200, France

  • Novartis Investigative Site

    Paris, 75013, France

  • Novartis Investigative Site

    Poitiers, 86021, France

  • Novartis Investigative Site

    Rennes, 35033, France

  • Novartis Investigative Site

    Regensburg, Bavaria, 93053, Germany

  • Novartis Investigative Site

    Dresden, Saxony, 01307, Germany

  • Novartis Investigative Site

    Leipzig, Saxony, 04289, Germany

  • Novartis Investigative Site

    Essen, 45147, Germany

  • Novartis Investigative Site

    Pécs, Baranya, 7623, Hungary

  • Novartis Investigative Site

    Debrecen, Hajdu Bihar Megye, 4032, Hungary

  • Novartis Investigative Site

    Budapest, H 1096, Hungary

  • Novartis Investigative Site

    Budapest, H-1083, Hungary

  • Novartis Investigative Site

    Ahmedabad, Gujarat, 380054, India

  • Novartis Investigative Site

    Lucknow, Uttar Pradesh, 226003, India

  • Novartis Investigative Site

    Vilnius, LT-08406, Lithuania

  • Novartis Investigative Site

    Singapore, 119074, Singapore

  • Novartis Investigative Site

    Santiago Compostela, A Coruna, 15706, Spain

  • Novartis Investigative Site

    Badalona, Barcelona, 08916, Spain

  • Novartis Investigative Site

    Barcelona, Catalonia, 08907, Spain

  • Novartis Investigative Site

    Madrid, 28006, Spain

  • Novartis Investigative Site

    Taipei, 10002, Taiwan

Conditions

Explore the condition pages connected to this study.