Fasting two days a week could shrink fatty liver, new study hopes to prove
NCT ID NCT07530809
First seen Apr 19, 2026 · Last updated Jun 23, 2026 · Updated 12 times
Summary
This study tests whether a 5:2 intermittent fasting diet (eating only about 600 calories on two non-consecutive days each week) can reduce liver fat in people with metabolic dysfunction-associated steatotic liver disease (MASLD). 120 adults with obesity and significant liver fat will be randomly assigned to either the fasting diet or a standard healthy diet for comparison. The main goal is to see if liver fat decreases after the diet period.
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Department of Internal Medicine II, Saarland University Medical Center, Saarland University,
RECRUITINGHomburg, Saarland, 66424, Germany
Contact
Contact Phone: •••-•••-•••• Email: •••••@•••••
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
time-restricted feeding (5:2 intermittent fasting diet)
What this could lead to
If it works, this could offer a simple, drug-free way to reduce liver fat and improve metabolic health in people with fatty liver disease.
What could go wrong
This is a small, early-stage behavioral study with no blinding. Results may not apply to everyone, and sticking to the diet long-term can be challenging.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.