Time-Restricted eating may beat cancer fatigue, new study hopes
NCT ID NCT06482515
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests whether eating all food within a 10-hour window each day can reduce severe, long-lasting fatigue in blood cancer survivors. About 96 adults who finished cancer treatment at least 2 months ago will either follow this time-restricted eating plan or receive standard nutrition advice. The goal is to see if this simple diet change improves energy, daily function, and quality of life.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 2
Tests whether the treatment actually works, and watches for side effects, in a larger group.
- Participants
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About 96 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Nov 2024
- Expected to finish
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Aug 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria (Participants must…): * Have a diagnosis of a hematologic neoplasm (e.g., leukemia, lymphoma, multiple myeloma); * Be at least 2 months post-treatment with chemotherapy, radiation, targeted therapy, chimeric antigen receptor (CAR)-T cell therapy, stem cell transplant, or another therapy (maintenance therapies are okay; steady unchanged treatment for relapsed disease for \>2 months and expected to stay on it until progression is okay); * Have a baseline level of fatigue, as determined by at least one of the following: 1. Reporting a score of 4 or higher in response to the question, "What was your worst fatigue in the last week, on a scale of 0-10, where 0 is no fatigue and 10 is the worst fatigue?" 2. In the habit of taking daytime naps, 3. Have fatigue that interferes with their ability to work, engage in social events, or is more than would be expected from physical exertion, * Be able to speak and/or read and write in English or Spanish; * Be at least 18 years old; and * Be able to provide informed consent. Exclusion criteria (participants must not…) * Be underweight, as defined as a body mass index \<18.5 kg/m2; * Already eat all their food within a window that is 10 h or shorter most (6/7) days of the week; * Be employed in a job where they regularly work away from the home at night (e.g., night shift); * Have surgery planned during the study duration; * Have any contraindications to the proposed nutrition intervention as identified by their medical provider, their designee, or the study team (e.g., type 1 diabetes, risk for hypoglycemia, medication requirements, pregnancy, breastfeeding, recent history of an eating disorder); * Be taking insulin; or * Be on enteral or parenteral nutrition.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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University of Maryland, Baltimore
RECRUITINGBaltimore, Maryland, 21201, United States
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