Tilt table test could be key to stopping fainting spells
NCT ID NCT07459478
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether a tilt table test, which provokes fainting in a controlled setting, can help people with vasovagal syncope (common fainting) reduce future episodes. About 238 adults will be randomly assigned to receive biofeedback training either with or without the tilt table test. The goal is to see if the test leads to fewer fainting episodes and better quality of life.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- tilt table testing
- What this could lead to
- If successful, this could show that tilt table testing helps people with fainting spells avoid future episodes when combined with biofeedback.
- What could go wrong
- This is a relatively small, early-stage trial. The tilt table test may not reduce fainting more than biofeedback alone, and results may not apply to all types of fainting.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 238 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Oct 2025
- Expected to finish
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Mar 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * All patients \>18 years of age with certain/highly likely vasovagal syncope after the guideline based syncope evaluation Exclusion Criteria: * Those aged \<18 years * Any patient diagnosed with another form of reflex syncope other than vasovagal syn-cope * Contraindication for tilt table testing at the discretion of the responsible physician * Those with a learning disability * Those presenting with pre-syncope and not with complete loss of consciousness * Those who are unwilling to provide informed consent * Those already diagnosed prior to evaluation who are referred for specific treatment op-tions
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Amsterdam UMC
RECRUITINGAmsterdam, Netherlands
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