Thyme honey soothes dry mouth in ICU patients, study finds
NCT ID NCT07358494
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether diluted thyme honey can reduce dry mouth in intensive care patients receiving oxygen therapy. 64 adults were randomly assigned to get oral care with either diluted thyme honey or standard salt water. After three days, the honey group reported less dry mouth and related symptoms like thirst and bad taste. The results suggest a simple, natural option for comfort in the ICU.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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64 people
The number who actually took part.
- Started
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Oct 2022
- Finished
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Nov 2022
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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Children (under 18), adults (18 to 64) and older adults (65 and over)
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Being treated under intensive care conditions and receiving nasal oxygen flow therapy above 4L/min, * Over 18 years of age, * Not diagnosed with Sjögren's Syndrome, * No previous exposure to radiotherapy or chemotherapy, * Has not had a salivary gland infection, * Has not undergone an operation to remove the salivary glands, * Not allergic to honey, * No chewing or swallowing difficulties, * Not using thyme-containing products for oral care in the previous period, * Patients who did not have any communication problems and who voluntarily agreed to participate in the study were included in the study Exclusion Criteria: \- Patients who did not meet the inclusion criteria and did not voluntarily agree to participate in the study were excluded.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Ankara University Institute of Health Sciences Department of Nursing
Ankara, Dışkapı, 6070, Turkey (Türkiye)
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