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Thumb arthritis study probes the Brain-Body connection

NCT ID NCT07447323

Knowledge-focused Sponsor: Hacettepe University Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at how accurately people with thumb base osteoarthritis can sense their thumb's position and movement. Researchers will compare these measurements between 100 participants with arthritis and healthy volunteers. No treatment is given; the goal is simply to understand how the condition affects the sense of position in the thumb.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Participants

About 100 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2025

Expected to finish

May 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Who is studied

Adults aged 25-75 years with trapeziometacarpal (TMC) osteoarthritis and healthy controls will be included in this cross-sectional case-control study. The TMC OA group will be radiographically classified according to the Eaton-Littler staging system (Stages I-IV). The target sample is 100 participants in the OA group (20 per stage) and 20 healthy controls. Participants will be recruited from the Faculty of Physiotherapy and Rehabilitation, Department of Orthopedic Physiotherapy and Rehabilitation, Hacettepe University (Ankara, Turkey). All participants will undergo standardized assessments of thumb proprioception and related clinical measures.

Ages

25 to 75 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria (TMC OA group): * Voluntary participation * Radiographic Eaton-Littler stage I-IV confirmed by an orthopedic specialist * Symptom duration ≥6 months * Age 25-75 years * Pain intensity ≥4/10 on the Visual Analog Scale (VAS) during daily activities at assessment * Ability to actively perform ≥40° palmar abduction * Adequate cognitive capacity to understand and perform study procedures (for participants aged ≥65 years: Montreal Cognitive Assessment \[MoCA\] score ≥21) Inclusion Criteria (Control group): * Voluntary participation * No thumb pain * Age 25-75 years * No clinical signs of TMC OA * Negative provocation tests * Adequate cognitive capacity to understand and perform study procedures (for participants aged ≥65 years: MoCA score ≥21) Exclusion Criteria (TMC OA group): * Inability to abduct the thumb beyond 40° due to severe pain/deformity (especially advanced stage III-IV) * Acute trauma or prior surgery of the hand/wrist * Conservative treatment for hand/thumb pain in the same extremity within the previous 6 months * Current use of anti-inflammatory medication * Peripheral nerve disorders affecting proprioception (e.g., carpal tunnel syndrome, dorsal radial nerve irritation, cervical radiculopathy, double crush syndrome) * Concomitant upper-extremity musculoskeletal disorders (e.g., trigger finger, De Quervain's disease) * Generalized joint hypermobility (Beighton score ≥4) * Neuromuscular, systemic peripheral neuropathic, autoimmune, rheumatic, or infectious diseases * Active malignancy * Neurological conditions affecting pain perception * Visual impairment * Pregnancy Exclusion Criteria (Control group): -Exclusion criteria identical to the TMC OA group

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Conditions

The condition(s) this trial relates to.

osteoarthritis, hand Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Trapeziometacarpal osteoarthritis

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Hacettepe University

    RECRUITING

    Ankara, Ankara, 06100, Turkey (Türkiye)

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