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New laser study breaks down kidney stone treatment success

NCT ID NCT07153978

Disease control Sponsor: Muharrem Baturu Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at how well a thulium fiber laser breaks up large kidney stones (over 1000 mm³) during a minimally invasive procedure called retrograde intrarenal surgery. Researchers tracked 81 patients to see what factors, like stone density, affect whether all fragments are cleared. The goal is to help doctors choose the best treatment approach for each patient.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Thulium fiber laser (TFL) lithotripsy device
What this could lead to
If successful, this could help doctors better predict which patients with large kidney stones will benefit most from thulium laser treatment, improving stone clearance and reducing repeat procedures.
What could go wrong
This is a small, single-center study with no control group, so results may not apply to all patients. The laser itself is already in use, so this trial mainly refines knowledge rather than proving a new breakthrough.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

81 people

The number who actually took part.

Started

Nov 2023

Finished

Jun 2025

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Patients ≥18 years of age * Presence of kidney stones larger than 1000 mm³ * Patients with single or multiple kidney stones * Patients eligible for retrograde intrarenal surgery (RIRS) Exclusion Criteria: * Patients younger than 18 years * Pregnant or breastfeeding women * Patients with uncorrected coagulopathy * Patients with active urinary tract infection * Patients with severe anatomic abnormalities preventing RIRS * Patients unwilling or unable to provide informed consent

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Conditions

The condition(s) this trial relates to.

Kidney Calculi nephrolithiasis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Renal stones Retrograde intrarenal surgery Thulium fiber laser

Contacts and locations

Locations

  • University of Gaziantep

    Gaziantep, Şehitkamil, 27310, Turkey (Türkiye)

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