Massive study aims to perfect testicular cancer aftercare
NCT ID NCT02229916
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study follows 6,900 men treated for testicular cancer to find the best way to detect cancer return and manage long-term side effects. Participants will have regular check-ups using scans, blood tests, and exams. The goal is to create standard follow-up guidelines that catch relapses early while avoiding unnecessary tests and radiation.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 6,900 people
The number the study aims to enrol. It can still change while the study runs.
- Start date
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Dec 2013
- Expected to finish
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Dec 2033
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
Consecutive patients with testicular cancer of any type and any stage and any age (incident cases). Testicular cancers are generally classified as seminomatous (seminoma) and nonseminomatous germ cell tumours (nonseminoma) of the testis. Mixed germ cell tumours belong to the group of non-seminomas. The stage of disease and the choice of treatment (active surveillance vs. chemotherapy vs. radiotherapy) define the risk of relapse, the pattern of relapse and the long-term toxicities. Staging in testicular cancer is performed according to the American Joint Committee on Cancer (AJCC) TNM staging system for testis cancer \[46\]. Metastatic testicular cancers are classified according to the International Germ Cell Cancer Collaborative Group (IGCCCG) risk groups \[47\].
- Ages
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18 years and older
- Sex
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Male participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Written informed consent. * Histologically proven seminomas or non-seminoma. * Seminoma: complete remission (CR) or lymph nodes (LN) \< 3cm or PET negative partial remission (PR) or non-seminoma: CR. * Completion of treatment within the last 6 months. * Patient able and willing to attend for regular surveillance. Exclusion Criteria: * Co-existent malignancy within 5 years. * Inability for any reason to comply with the trial investigations or follow-up schedules.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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Kantonsspital St.Gallen; Onkologie/Haematologie
RECRUITINGSankt Gallen, 9007, Switzerland
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