Electric eye therapy: can a home device slow blindness?
NCT ID NCT07531927
First seen Jun 27, 2026 · Last updated Jul 29, 2026 · Updated 2 times
Summary
This study tests if a device that delivers mild electrical pulses to the eye (transcorneal electrical stimulation) can safely slow the progression of geographic atrophy, an advanced form of age-related macular degeneration that causes vision loss. About 70 people aged 60 and older will use the device at home for 30 minutes once a week for a year. The study compares two different types of electrical stimulation against a sham (placebo) treatment to see which works best.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 70 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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May 2026
- Expected to finish
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Jun 2028
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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60 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria: * Willing and able to understand the study and provide informed consent * 60 years of age or older * Diagnosis of geographic atrophy due to age-related macular degeneration confirmed by imaging * The affected area in the eye must be within a defined size range and clearly visible on imaging * Eye conditions must allow for good-quality images and reliable measurements * Must have a minimum level of visual acuity * Women of childbearing potential must have a negative pregnancy test, and must agree to use effective contraception during the study (women who are postmenopausal or surgically sterile are not subject to pregnancy-related requirements) Exclusion criteria: * History or presence of certain eye conditions (e.g. macular edema, abnormal blood vessel growth or related conditions, retinal detachment, blood vessel blockage) in the study eye * Previous major eye surgeries (including retinal surgery or vitrectomy) * Previous laser treatment or injections in the study eye * Any other eye condition that could interfere with vision tests, imaging or study results * Planned eye surgery during the study period * Recent treatment with investigational drugs for geographic atrophy * Presence of active medical implants * Serious or uncontrolled systemic diseases, history of epilepsy or poor general health or conditions affecting the ability to follow study procedures * Participation in another clinical study recently or at the same time * Breastfeeding, relevant allergies (e.g. to silver), or heavy smoking
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Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The study's own enquiry address
This study publishes an address for enquiries. See it below .
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The places running it
5 sites. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Show contact details
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Genom att skicka in godkänner du våra Användarvillkor
Study contacts
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Contact
Email: •••••@•••••
Locations
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Centre for Ophthalmology, University Hospital Tuebingen
RECRUITINGTübingen, 72076, Germany
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Department of Ophthalmology, Klinikum Stuttgart
RECRUITINGStuttgart, 70174, Germany
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Department of Ophthalmology, Ludwig-Maximilians-University Munich
RECRUITINGMünchen, 80336, Germany
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Department of Ophthalmology, University Hospital Ulm
NOT_YET_RECRUITINGUlm, 89075, Germany
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Department of Ophthalmology, University Medical Center Hamburg-Eppendorf
RECRUITINGHamburg, 20246, Germany
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Other studies related to the condition(s) this trial covers.
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