New group therapy shows promise for easing anxiety and depression
NCT ID NCT06863948
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested a new type of group therapy called Terebenin's Method for adults with mild to moderate anxiety and depression. The therapy combines role-playing, body awareness, and guided discussion in weekly sessions over 8 weeks. Researchers measured changes in symptoms and stress-related biomarkers like cortisol. The goal was to see if this approach could help reduce anxiety and depression and to gather data for a larger future study.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Terebenin's Method (integrative group psychotherapy combining psychodrama, systemic constellation, body-oriented practices, and directive therapy)
- What this could lead to
- If it works, this could offer a new group therapy option for people with mild to moderate anxiety and depression, potentially reducing symptoms and stress.
- What could go wrong
- This is a small pilot study with only 66 participants, so results may not apply to everyone. It's early-stage research, and the therapy may not prove more effective than standard treatments.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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66 people
The number who actually took part.
- Started
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May 2024
- Finished
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Oct 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 60 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adults aged 18-60. * Subclinical, mild, or moderate anxiety/depressive symptoms (screened via HADS, BDI-II, STAI). * No current psychotropic medication use or on a stable dose for ≥4 weeks with no planned changes. * Ability to attend weekly group sessions for 8 weeks + follow-up visits, including saliva sample collection. * Provision of written informed consent. Exclusion Criteria: * Severe psychiatric disorders (e.g., schizophrenia, bipolar disorder in a manic phase, major depression with psychotic features). * Significant suicidal risk requiring urgent intervention. * Severe somatic illness impeding participation. * Active substance use disorder unless in stable remission for \>6 months. * Ongoing psychotherapy that could confound results. * Inability to comply with saliva collection (e.g., shift work, severe sleep disturbances).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Center for New Medical Technologies
Novosibirsk, 630090, Russia
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