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Could hormone therapy replace chemo for some breast cancer patients?

NCT ID NCT07084558

First seen Nov 01, 2025 · Last updated May 22, 2026 · Updated 22 times

Summary

This study tests whether hormone therapy works as well as chemotherapy for people with a common type of early breast cancer (HR-positive, HER2-negative) that shows no signs of cancer DNA in the blood. About 350 participants will first take a hormone pill for 3 weeks to see if their tumor responds. If it does, they are randomly assigned to either continue hormone therapy or switch to chemotherapy for several months. The goal is to see if hormone therapy can control the cancer just as well while causing fewer side effects and improving quality of life.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Allg. Gynäkologie u. gyn. Onkologie/Senologie

    RECRUITING

    Vienna, Austria, 1190, Austria

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Dornbirn BGZ; Frauenheilkunde u. Geburtshilfe

    ACTIVE_NOT_RECRUITING

    Dornbirn, Austria

  • Hanusch Krankenhaus, 3. Medizinische Abteilung

    ACTIVE_NOT_RECRUITING

    Vienna, Austria

  • KH BHB St. Veit/Glan Brustzentrum Kärnten

    ACTIVE_NOT_RECRUITING

    Sankt Veit an der Glan, Austria

  • Klinik Hietzing, Gyn. Abteilung; Karl Landsteiner Institut f. gyn. Onkologie u. Senologie

    ACTIVE_NOT_RECRUITING

    Vienna, Austria

  • LKH Salzburg - PMU, Univ.Klinik f. Innere Medizin III / SCRI CCCIT

    NOT_YET_RECRUITING

    Salzburg, Austria

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • Landesklinikum Baden BGZ; Abt. f. Allgemein- u. Viszeralchirurgie

    ACTIVE_NOT_RECRUITING

    Baden, Austria

  • Landeskrankenhaus Feldkirch Interne E

    ACTIVE_NOT_RECRUITING

    Feldkirch, Austria

  • MUG - LKH Graz Klin. Abt. f. Onkologie

    ACTIVE_NOT_RECRUITING

    Graz, Austria

  • MUG - Univ. Frauenklinik Graz, Gyn. Abteilung

    ACTIVE_NOT_RECRUITING

    Graz, Austria

  • MUI - Univ. Klinik f. Frauenheilkunde Innsbruck Klin. Abteilung f. Gynäkologie u. Geburtshilfe

    RECRUITING

    Innsbruck, Austria

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

  • TumorZentrum Kepler Universitätsklinikum Linz

    ACTIVE_NOT_RECRUITING

    Linz, Austria

  • Universitätsklinikum St. Pölten, Klin. Abteilung f. Innere Medizin 1

    ACTIVE_NOT_RECRUITING

    Sankt Pölten, Austria

  • Universitätsklinikum Wiener Neustadt, Abteilung für Innere Medizin, Hämatologie und int. Onkologie

    NOT_YET_RECRUITING

    Wiener Neustadt, Austria

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.