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Shocking the nerve: which stimulation works better?

NCT ID NCT07247721

Knowledge-focused Sponsor: University of Castilla-La Mancha Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested two electrical nerve stimulation techniques—TENS (through skin) and PENS (via needles)—on 120 healthy adults to see how they affect pain thresholds and wrist strength. Each person received one 20-minute session. The goal is to understand which method works better and how they compare to placebo, helping doctors make informed choices for pain management.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

What this could lead to
If successful, this research could help clinicians choose between TENS and PENS for pain relief and nerve stimulation based on stronger evidence.
What could go wrong
This is a small, early-stage study in healthy people, not patients. Results may not apply to real-world pain conditions, and the effects measured are short-term.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

120 people

The number who actually took part.

Started

Jan 2026

Finished

Apr 2026

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 60 years

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Healthy volunteers aged between 18 and 60 years. * No history of musculoskeletal or neurological disorders. * No alterations in sensitivity in the upper limb. * Not taking any medication in the previous two weeks. * Able to understand the study procedures and provide informed consent. Exclusion Criteria: * Any neurological or neuromuscular disease. * History of upper limb trauma, surgery, or persistent pain. * Contraindications to electrical stimulation or invasive techniques. * Presence of cardiac pacemaker, epilepsy, diabetes, cancer, or cardiovascular disease. * Skin lesions or infections in the stimulation area. * Pregnancy or suspected pregnancy.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Nerve stimulation Pain modulation Sensorimotor function

Contacts and locations

Locations

  • Universidad de Castilla La Mancha

    Toledo, Toledo, 45071, Spain

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