New hope for lung cancer: targeted drug telisotuzumab vedotin faces off against chemo
NCT ID NCT04928846
First seen Jun 24, 2026 · Last updated Sep 17, 2026 · Updated 9 times
Summary
This phase 3 trial compares a new targeted drug, telisotuzumab vedotin, to the standard chemotherapy docetaxel in adults with a specific type of advanced non-small cell lung cancer that has a high level of a protein called c-Met. About 698 participants worldwide will receive either the new drug or chemo to see which works better at slowing cancer growth and improving survival. The study is currently recruiting.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- telisotuzumab vedotin (an antibody-drug conjugate targeting c-Met)
- What this could lead to
- If successful, this could offer a new targeted treatment option for people with a specific type of lung cancer that has stopped responding to prior therapy.
- What could go wrong
- This is a phase 3 trial, but the drug is still investigational. It may not prove better than the current standard docetaxel, and side effects from the targeted therapy could be significant.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
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About 768 people
The number the study aims to enrol. It can still change while the study runs.
- Started
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Mar 2022
- Expected to finish
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Feb 2029
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Projected life expectancy of at least 12 weeks. * Participants must have c-Met overexpressing non-small cell lung cancer (NSCLC) as assessed by an AbbVie designated immunohistochemistry (IHC) laboratory using the VENTANA MET (SP44) RxDx assay. * Archival or fresh tumor material must be submitted for assessment of c-Met protein expression levels during the Pre-Screening period. Tumor material from the primary tumor site and/or metastatic sites are allowed. * If a participant was prescreened for Study M14-239 but did not enroll, tumor material previously submitted for Study M14-239 may be used for Study M18-868 Pre-Screening upon confirmation from AbbVie that sufficient evaluable tumor material is available (Except China). * A histologically or cytologically documented non-squamous cell NSCLC that is locally advanced or metastatic. * A known epidermal growth factor receptor (EGFR) activating mutation status. \-- Participants with EGFR activating mutations are not eligible * Actionable alterations in genes other than EGFR are eligible. * Measurable disease per Response Evaluation Criteria in Solid Tumors (RECIST) version 1.1. * An Eastern Cooperative Oncology Group (ECOG) Performance Status of 0 to 1. * Have received no more than 1 line of prior systemic cytotoxic chemotherapy in the locally advanced or metastatic setting. * Have progressed on at least 1 line of prior therapy for locally advanced/metastatic NSCLC * Participants WITHOUT an actionable gene alteration: must have progressed on (or be considered ineligible for) platinum-based chemotherapy and immune checkpoint inhibitor (as monotherapy or in combination with chemotherapy). * Participants WITH an actionable gene alteration for which immune checkpoint inhibitor therapy is not standard of care (e.g., anaplastic lymphoma kinase \[ALK\] translocation): must have progressed on (or be considered ineligible for) anti-cancer therapy targeting driver gene alterations and platinum-based chemotherapy. * Participants with gene alterations for which immune checkpoint inhibitor is standard of care must have also progressed on (or be considered ineligible for) immune checkpoint inhibitor (as monotherapy or in combination with chemotherapy). * Must be considered appropriate for docetaxel therapy based on the assessment of the treating physician. * Participants with metastases to the central nervous system (CNS) are eligible only after adequate treatment (such as surgery, radiotherapy, or drug therapy) is provided and: * They are asymptomatic and off or on a stable or reducing dose of systemic steroids (on no more than 10 mg per day \[QD\] prednisone or equivalent) and/or anticonvulsants for at least 2 weeks prior to randomization. Exclusion Criteria: * Evidence of new, untreated CNS metastases or progressing CNS metastases after treatment. * Evidence of leptomeningeal disease. * Participants with adenosquamous or neuroendocrine histology, nor sarcomatoid features. * Epidermal growth factor receptor (EGFR) activating mutations. * Participants who have received prior c-Met-targeted antibodies, prior telisotuzumab vedotin, or prior antibody-drug conjugates either targeting c-Met or consisting of monomethylauristatin E.. * Participants who have received prior docetaxel therapy. * A history of other malignancies except: * Malignancy treated with curative intent and with no known active disease present for \>=2 years before the first dose of study drug and felt to be at low risk for recurrence by investigator. Additionally, participants must not be receiving any ongoing anti-cancer therapy, including maintenance therapy, prior to randomization.. * Adequately treated non-melanoma skin cancer or lentigo maligna without evidence of disease. * Adequately treated carcinoma in situ without current evidence of disease. * A history of idiopathic pulmonary fibrosis, organizing pneumonia (e.g., bronchiolitis obliterans), drug-induced pneumonitis, or idiopathic pneumonitis, evidence of active pneumonitis on screening chest computed tomography (CT) scan or prior pneumonectomy. A history of prior radiation pneumonitis in the radiation field (fibrosis) is not permitted. * Unresolved nor adverse event (AE) \>= Grade 2 from prior anticancer therapy, except for alopecia or anemia. Participants with hormone deficiencies caused by prior anticancer therapy who are asymptomatic and on a stable dose of replacement hormone are eligible for study. * Major surgery within 21 days prior to randomization. * Clinically significant condition(s) as listed in the protocol.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Non-small cell lung cancer are added.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
263 sites in 31 countries. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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AP-HP - Hopital Tenon /ID# 239179
RECRUITINGParis, 75020, France
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APHM - Hopital Nord /ID# 251935
RECRUITINGMarseille, Bouches-du-Rhone, 13015, France
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ASST Sette Laghi - Ospedale Di Circolo E Fondazione Macchi Varese /ID# 238536
RECRUITINGVarese, 21100, Italy
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AZ Maria Middelares /ID# 246768
RECRUITINGGhent, 9000, Belgium
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Adana Acıbadem Hospital /ID# 234208
COMPLETEDAdana, 01130, Turkey (Türkiye)
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Adana Sehir Egitim ve Arastirma Hastanesi /ID# 255638
RECRUITINGAdana, 01060, Turkey (Türkiye)
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AdventHealth Hendersonville /ID# 265349
COMPLETEDHendersonville, North Carolina, 28792, United States
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Affiliated Cancer Hospital of Guangxi Medical University /ID# 231855
RECRUITINGNanning, Guangxi, 530021, China
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Affiliated Hospital of Guangdong Medical College /ID# 233317
RECRUITINGZhanjiang, Guangdong, 524004, China
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Affiliated Hospital of Hebei University /ID# 239586
RECRUITINGBaoding, Hebei, 071000, China
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Ajou University Hospital - Suwon-si /ID# 233319
RECRUITINGSuwon, Gyeonggido, 16499, South Korea
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Algemeen Ziekenhuis klina /ID# 239853
RECRUITINGBrasschaat, Antwerpen, 2930, Belgium
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Alliance for Multispecialty Research (AMR) - Kansas City /ID# 247567
COMPLETEDKansas City, Missouri, 64114-4859, United States
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Anhui Medical University - Anhui Chest Hospital /ID# 231899
RECRUITINGHefei, Anhui, 230032, China
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Ankara City Hospital /ID# 234210
RECRUITINGAnkara, 06800, Turkey (Türkiye)
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Asklepios Fachkliniken Muenchen-Gauting /ID# 272768
RECRUITINGGauting, Bavaria, 82131, Germany
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Astera Cancer Care /ID# 257753
COMPLETEDEast Brunswick, New Jersey, 08816-4096, United States
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Austin Health /ID# 247507
RECRUITINGHeidelberg, Victoria, 3084, Australia
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Avera Cancer Institute - Aberdeen /ID# 257759
COMPLETEDAberdeen, South Dakota, 57401, United States
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Avera Cancer Institute /ID# 239635
COMPLETEDSioux Falls, South Dakota, 57105, United States
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Azienda Ospedaliera Complesso Ospedaliero San Giovanni-Addolorata /ID# 238618
RECRUITINGRome, Roma, 00184, Italy
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Azienda Ospedaliera Papardo /ID# 258038
COMPLETEDMessina, 98158, Italy
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Azienda Ospedaliera Universitaria Luigi Vanvitelli /ID# 252942
RECRUITINGNaples, Napoli, 80138, Italy
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Azienda Ospedaliera di Perugia - Ospedale S. Maria della Misericordia /ID# 238473
RECRUITINGPerugia, 06156, Italy
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Azienda Socio Sanitaria Territoriale di Cremona /ID# 238698
RECRUITINGCremona, 26100, Italy
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BRCR Medical Center Inc /ID# 262344
COMPLETEDTamarac, Florida, 33321-2919, United States
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Bagcilar Medipol Mega Universite Hastanesi /ID# 234211
RECRUITINGIstanbul, 34214, Turkey (Türkiye)
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Baptist Health Lexington /ID# 252769
COMPLETEDLexington, Kentucky, 40503, United States
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Barwon Health /ID# 241920
RECRUITINGGeelong, Victoria, 3220, Australia
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Beijing Cancer Hospital /ID# 231923
RECRUITINGBeijing, Beijing Municipality, 100142, China
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Beijing Chest Hospital, Capital Medical University /ID# 232202
RECRUITINGBeijing, Beijing Municipality, 101149, China
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CHA Bundang Medical Center /ID# 233318
RECRUITINGSeongnam, Gyeonggido, 13496, South Korea
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CHU Insular-Materno Infantil /ID# 255094
RECRUITINGLas Palmas de Gran Canaria, Las Palmas, 35016, Spain
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CHU Lille - Hôpital Albert Calmette /ID# 251934
RECRUITINGLille, Hauts-de-France, 59037, France
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CHU de Liege /ID# 246772
RECRUITINGLiège, 4000, Belgium
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CISSS de la Monteregie /ID# 239081
RECRUITINGGreenfield Park, Quebec, J4V 2H1, Canada
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CSSS Alphonse-Desjardins, CHAU de Levis /ID# 261158
RECRUITINGLévis, Quebec, G6V 3Z1, Canada
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Cancer Care Associates Of York /ID# 266143
COMPLETEDYork, Pennsylvania, 17403, United States
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Cancer Hospital of Shantou University Medical College /ID# 242182
RECRUITINGShantou, Guangdong, 515041, China
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Cardiomed Srl /Id# 255320
RECRUITINGCluj-Napoca, Cluj, 400015, Romania
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Casa de Saúde Santa Marcelina /ID# 231605
RECRUITINGSão Paulo, 08270-070, Brazil
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Cemic /Id# 231486
RECRUITINGCiudad Autonoma Buenos Aires, Buenos Aires, 1431, Argentina
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Centre Hosp Intercommunal de Creteil /ID# 251936
RECRUITINGCréteil, Val-de-Marne, 94000, France
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Centre Hospitalier Universitaire de Bordeaux /ID# 244953
RECRUITINGPessac, New Aquitaine, 33604, France
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Centre Hospitalier d'Avignon /ID# 275229
RECRUITINGAvignon, Provence-Alpes-Côte d'Azur Region, 84000, France
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Centre Leon Berard /ID# 267397
RECRUITINGLyon, Rhone, 69373, France
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Centro Hospitalar Universitario do Porto, EPE - Hospital Santo Antonio /ID# 241572
RECRUITINGPorto, 4099-001, Portugal
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Centro Médico Austral /ID# 239860
RECRUITINGCiudad Autonoma Buenos Aires, Buenos Aires F.D., 1019, Argentina
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Centro de Investigacion Clínica Chapultepec SA de CV /ID# 231928
COMPLETEDMorelia, Michoacán, 58260, Mexico
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Centro de Investigaciones Clinicas Clinica Viedma S.A. /ID# 232339
RECRUITINGViedma, Río Negro Province, 8500, Argentina
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Centrul Medical de Diagnostic si Tratament Ambulator Neomed SRL /ID# 240826
RECRUITINGBrasov, 500283, Romania
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Changhua Christian Hospital /ID# 238394
RECRUITINGChanghua City, Changhua County, 50006, Taiwan
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Charite Universitaetsmedizin Berlin Campus Virchow-Klinikum /ID# 234247
RECRUITINGBerlin, 13353, Germany
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Chugoku Central Hospital /ID# 242970
RECRUITINGFukuyama, Hiroshima, 720-0001, Japan
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Chung Shan Medical University Hospital /ID# 238444
RECRUITINGTaichung, 402, Taiwan
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Chungbuk National University Hospital /ID# 257891
RECRUITINGCheongju-si, North Chungcheong, 28644, South Korea
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City Of Hope - Antelope Valley /ID# 263138
RECRUITINGLancaster, California, 93534, United States
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City Of Hope - Seacliff /ID# 263143
RECRUITINGHuntington Beach, California, 92648, United States
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City of Hope - Orange County Lennar Foundation Cancer Center /ID# 263144
RECRUITINGIrvine, California, 92618, United States
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City of Hope /ID# 243157
RECRUITINGDuarte, California, 91010, United States
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Clinica Amo - Rio Vermelho /ID# 231604
RECRUITINGSalvador, Estado de Bahia, 41950-640, Brazil
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Clinica Universidad Catolica del Maule /ID# 231294
RECRUITINGTalca, Maule Region, 3461341, Chile
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Clinical Research & Oncology Oaxaca /ID# 231883
RECRUITINGOaxaca City, 68020, Mexico
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Community Cancer Trials of Utah - South Ogden /ID# 262829
COMPLETEDOgden, Utah, 84405-7194, United States
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Complex Cancer Center Plovdiv /ID# 234106
RECRUITINGPlovdiv, 4004, Bulgaria
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Complex Oncology Center - Burgas /ID# 240532
COMPLETEDBurgas, 8000, Bulgaria
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Cross Cancer Institute. /ID# 252065
RECRUITINGEdmonton, Alberta, T6G 1Z2, Canada
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Dana-Farber Cancer Institute /ID# 247132
COMPLETEDBoston, Massachusetts, 02215, United States
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Dell Seton Medical Center /ID# 247016
ACTIVE_NOT_RECRUITINGAustin, Texas, 78701, United States
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Dicle Universitesi Tip /ID# 234036
RECRUITINGDiyarbakır, 21200, Turkey (Türkiye)
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Disc_Barts Health NHS Trust - The Royal London Hospital /ID# 254342
RECRUITINGLondon, Greater London, E1 2ES, United Kingdom
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Dr. Suat Seren Gogus Has /ID# 262291
RECRUITINGIzmir, 35110, Turkey (Türkiye)
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Duplicate_Memphis VA Medical Center /ID# 263250
COMPLETEDMemphis, Tennessee, 38104, United States
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E-DA Cancer Hospital /ID# 239718
RECRUITINGKaohsiung City, Kaohsiung, 82445, Taiwan
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Edward-Elmhurst Cancer Center /ID# 238552
ACTIVE_NOT_RECRUITINGElmhurst, Illinois, 60126, United States
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Ege University Medical Faculty /ID# 234039
RECRUITINGIzmir, 35040, Turkey (Türkiye)
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Eisenhower Medical Center /ID# 233189
COMPLETEDRancho Mirage, California, 92270-3221, United States
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Fakultna nemocnica s poliklinikou F.D. Roosevelta Banska Bystrica /ID# 230084
COMPLETEDBanská Bystrica, Banská Bystrica Region, 975 17, Slovakia
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First Affiliated Hospital of China Medical University /ID# 231924
RECRUITINGShenyang, Liaoning, 110001, China
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FirstHealth of the Carolinas- Speciality Center /ID# 241279
COMPLETEDPinehurst, North Carolina, 28374, United States
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Fujian Provincial Cancer Hospital /ID# 243134
RECRUITINGFuzhou, Fujian, 350014, China
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Fujieda Municipal General Hospital /ID# 255155
RECRUITINGFujieda-shi, Shizuoka, 426-8677, Japan
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Fukushima Medical University /ID# 249691
RECRUITINGFukushima, 960-1295, Japan
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Fundacao Champalimaud /ID# 241925
RECRUITINGLisbon, Lisbon District, 1400-038, Portugal
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Fundacao Pio XII - Hospital de Cancer de Barretos /ID# 233247
RECRUITINGBarretos, São Paulo, 14784-400, Brazil
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Fundacion Arturo Lopez Perez /ID# 231151
RECRUITINGProvidencia, Santiago Metropolitan, 7500921, Chile
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Fundacion Ctic - Centro De Tratamiento E Investigacion Sobre Cancer Luis Carlos /ID# 258131
RECRUITINGBogotá, Bogota D.C., 110131, Colombia
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Gazi Universitesi /ID# 265425
RECRUITINGAnkara, 06560, Turkey (Türkiye)
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Genesis Cancer Care Center /ID# 239190
ACTIVE_NOT_RECRUITINGZanesville, Ohio, 43701-1406, United States
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Goshen Center for Cancer Care /ID# 257734
COMPLETEDGoshen, Indiana, 46526, United States
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Grand Hopital de Charleroi - Les Viviers /ID# 234178
RECRUITINGCharleroi, Hainaut, 6280, Belgium
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Gunma Prefectural Cancer Center /ID# 233723
RECRUITINGOta-shi, Gunma, 373-8550, Japan
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Gyeongsang National University Hospital /ID# 234244
RECRUITINGJinju, Gyeongsangnam-do, 52727, South Korea
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Haemato-Onkologie Hamburg /ID# 241047
RECRUITINGHamburg, 20251, Germany
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HagaZiekenhuis /ID# 243693
RECRUITINGThe Hague, South Holland, 2545 AA, Netherlands
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Harbin Medical University Cancer Hospital /Id# 231941
RECRUITINGHarbin, Heilongjiang, 150081, China
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Hattiesburg Clinic /ID# 248033
RECRUITINGHattiesburg, Mississippi, 39401, United States
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Henan Cancer Hospital /ID# 239577
RECRUITINGZhengzhou, Henan, 450008, China
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Henry Dunnant Hospital Center /ID# 267021
RECRUITINGAthens, Attica, 11526, Greece
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Hirosaki University Hospital /ID# 242377
RECRUITINGHirosaki-shi, Aomori, 036-8203, Japan
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Hiroshima University Hospital /ID# 241882
RECRUITINGHiroshima, Hiroshima, 734-8551, Japan
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Hokkaido University Hospital /ID# 241289
RECRUITINGSapporo, Hokkaido, 060-8648, Japan
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Hopital Arnaud de Villeneuve /ID# 239404
RECRUITINGMontpellier, Herault, 34295, France
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Hopital Du Sacre-Coeur De Montreal /ID# 274584
RECRUITINGMontreal, Quebec, H4J 1C5, Canada
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Hopitaux Universitaires Paris Centre-Hopital Cochin /ID# 239409
RECRUITINGParis, Paris, 75679, France
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Hospices Civils de Lyon - Hopital Louis Pradel /ID# 251933
RECRUITINGBron, Rhone, 69500, France
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Hospital Britanico de Buenos Aires /ID# 231495
RECRUITINGCiudad Autonoma de Buenos Aire, Buenos Aires, 1280, Argentina
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Hospital CUF Porto /ID# 241570
RECRUITINGPorto, 4100-180, Portugal
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Hospital Clinico Universidad De Los Andes /ID# 260974
RECRUITINGSantiago, 7501504, Chile
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Hospital Clinico Universitario de Valencia /ID# 240378
RECRUITINGValencia, 46010, Spain
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Hospital Da Crianca Santo Antonio /ID# 233249
RECRUITINGPorto Alegre, Rio Grande do Sul, 90020-090, Brazil
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Hospital La Louviere Site Jolimont - Helora /ID# 246771
RECRUITINGLa Louvière, Hainaut, 7100, Belgium
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Hospital Nuestra Senora de Sonsoles /ID# 255102
RECRUITINGÁvila, 05004, Spain
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Hospital Of The University Of Occupational And Environmental Health, Japan /ID# 241191
RECRUITINGKitakyushu-shi, Fukuoka, 807-8556, Japan
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Hospital Pablo Tobon Uribe /ID# 258128
RECRUITINGMedellín, Antioquia, 050034, Colombia
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Hospital Sirio Libanes - Sao Paulo /ID# 261827
RECRUITINGSão Paulo, 01308-050, Brazil
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Hospital Universitario 12 de Octubre /ID# 240176
RECRUITINGMadrid, 28041, Spain
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Hospital Universitario Dexeus - Grupo Quironsalud /ID# 255105
RECRUITINGBarcelona, 08028, Spain
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Hospital Universitario Fundacion Alcorcon /ID# 255100
RECRUITINGAlcorcón, Madrid, 28922, Spain
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Hospital Universitario de Fuenlabrada /ID# 255093
RECRUITINGFuenlabrada, Madrid, 28942, Spain
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Hospital Universitario de Jaen /ID# 240588
RECRUITINGJaén, 23007, Spain
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Hualien Tzu Chi Hospital /ID# 238398
RECRUITINGHualien City, 97002, Taiwan
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Hubei Cancer Hospital /ID# 240045
RECRUITINGWuhan, Hubei, 430079, China
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Hulston Cancer Center /ID# 232226
RECRUITINGSpringfield, Missouri, 65807-5287, United States
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Humanitas Istituto Clinico Catanese /ID# 273050
RECRUITINGMisterbianco, Catania, 95045, Italy
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Hunan Cancer Hospital /ID# 231943
RECRUITINGChangsha, Hunan, 410006, China
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I.R.C.C.S Istituto Tumori Giovanni Paolo II /ID# 238696
RECRUITINGBari, 70124, Italy
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IPO Porto FG, EPE /ID# 241569
RECRUITINGPorto, 4200-072, Portugal
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IRCCS Ospedale San Raffaele /ID# 254376
RECRUITINGMilan, Milano, 20132, Italy
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Ibaraki Prefectural Central Hospital /ID# 246145
RECRUITINGKasama-shi, Ibaraki, 309-1793, Japan
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Icegclinic /Id# 231212
RECRUITINGLa Florida, Santiago Metropolitan, 8241479, Chile
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Imat Oncomedica /ID# 258129
RECRUITINGMontería, Departamento de Córdoba, 230018, Colombia
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Inonu Universitesi Turgut Ozal /ID# 234038
RECRUITINGBattalgazi/malatya, 44280, Turkey (Türkiye)
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Institut Curie /ID# 240141
RECRUITINGParis, Paris, 75248, France
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Institut Gustave Roussy /ID# 267415
RECRUITINGVillejuif, Île-de-France Region, 94800, France
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Institut Jules Bordet /ID# 246770
RECRUITINGAnderlecht, 1070, Belgium
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Instituto Dor de Pesquisa e Ensino /ID# 233245
RECRUITINGRio de Janeiro, 22281-100, Brazil
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Instituto Nacional de Cancer (INCA) /ID# 231509
RECRUITINGRio de Janeiro, 20231-050, Brazil
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Instituto de Ensino e Pesquisas Sao Lucas /ID# 247417
RECRUITINGSão Paulo, 01236-030, Brazil
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Instituto de Oncologia Angel H Roffo /ID# 231499
RECRUITINGBuenos Aires, 1417, Argentina
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Institutul Regional de Oncologie /ID# 254065
RECRUITINGIași, 700483, Romania
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Instytut Centrum Zdrowia Matki Polki /ID# 239024
RECRUITINGLodz, Łódź Voivodeship, 93-338, Poland
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Interbalkan Medical Center Of Thessaloniki /ID# 254407
COMPLETEDThessaloniki, 57001, Greece
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Intermountain Health St Vincent Regional Hospital - Cancer Centers of Montana /ID# 253147
ACTIVE_NOT_RECRUITINGBillings, Montana, 59102, United States
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Investigative Clinical Research of Indiana - Indianapolis /ID# 260468
COMPLETEDIndianapolis, Indiana, 46260, United States
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Ironwood Cancer & Res Ctr /ID# 262446
ACTIVE_NOT_RECRUITINGChandler, Arizona, 85224-5665, United States
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Isala /ID# 238846
RECRUITINGZwolle, Overijssel, 8025 AB, Netherlands
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Iwate Medical University Hospital /ID# 239027
RECRUITINGShiwa-gun, Iwate, 028-3695, Japan
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Izmir Ekonomi Universitesi Ozel Medicalpoint Hastanesi /ID# 234209
RECRUITINGCordaleo, İzmir, 35575, Turkey (Türkiye)
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Jeroen Bosch Ziekenhuis /ID# 234087
RECRUITING's-Hertogenbosch, 5223 GZ, Netherlands
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Jessa Ziekenhuis /ID# 246766
RECRUITINGHasselt, Limburg, 3500, Belgium
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Jilin Cancer Hospital /ID# 244702
RECRUITINGChangchun, Jilin, 130012, China
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Jinan Central Hospital /ID# 231895
RECRUITINGJinan, Shandong, 250013, China
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Juntendo University Hospital /ID# 239932
RECRUITINGBunkyo-ku, Tokyo, 113-8431, Japan
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Kaiser Permanente Moanalua Medical Center /ID# 238363
RECRUITINGHonolulu, Hawaii, 96819-1469, United States
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Kanagawa Cardiovascular and Respiratory Center /ID# 239052
RECRUITINGYokohama, Kanagawa, 236-0051, Japan
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Kangbuk Samsung Hospital /ID# 233711
RECRUITINGSeoul, Seoul Teugbyeolsi, 03181, South Korea
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Kansai Medical University Hospital /ID# 233476
RECRUITINGHirakata-shi, Osaka, 573-1191, Japan
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Karolinska University Hospital Solna /ID# 229853
RECRUITINGSolna, Stockholm County, 171 64, Sweden
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Keio University Hospital /ID# 239506
RECRUITINGShinjuku-ku, Tokyo, 160-8582, Japan
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Kindai University Hospital /ID# 239085
RECRUITINGSakai-shi, Osaka, 590-0197, Japan
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Kitasato University Hospital /ID# 239958
RECRUITINGSagamihara-shi, Kanagawa, 252-0375, Japan
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Klinik Floridsdorf /ID# 230608
RECRUITINGVienna, State of Vienna, 1210, Austria
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Klinik Penzing /ID# 230700
RECRUITINGVienna, State of Vienna, 1140, Austria
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Klinikum Kassel /ID# 240142
RECRUITINGKassel, Hesse, 34125, Germany
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Klinikum Wels-Grieskirchen Gmbh /ID# 249000
RECRUITINGWels, Upper Austria, 4600, Austria
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Kobe Minimally Invasive Cancer Center /ID# 254131
RECRUITINGKobe, Hyōgo, 650-0046, Japan
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Kumamoto University Hospital /ID# 241039
RECRUITINGKumamoto, Kumamoto, 8608556, Japan
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Kurashiki Central Hospital /ID# 239344
RECRUITINGKurashiki-shi, Okayama-ken, 710-8602, Japan
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Kurume University Hospital /ID# 254900
RECRUITINGKurume-shi, Fukuoka, 830-0011, Japan
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LC Investigacion /ID# 239880
RECRUITINGBuenos Aires, 1125, Argentina
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Landeskrankenhaus Feldkirch /ID# 250333
RECRUITINGFeldkirch, Vorarlberg, 6800, Austria
-
Landeskrankenhaus Salzburg-Universitaetsklinikum der PMU (LKH) /ID# 232467
RECRUITINGSalzburg, 5020, Austria
-
LinYi Cancer Hospital /ID# 239713
RECRUITINGLinyi, Shandong, 276001, China
-
MRUK-MED I Sp. z o.o. /ID# 239363
RECRUITINGRzeszów, Podkarpackie Voivodeship, 35-021, Poland
-
Maastricht Universitair Medisch Centrum /ID# 233932
RECRUITINGMaastricht, Limburg, 6229 HX, Netherlands
-
Mackay Memorial Hospital /ID# 238392
RECRUITINGTaipei, 104, Taiwan
-
Maimonides Medical Center /ID# 240783
ACTIVE_NOT_RECRUITINGBrooklyn, New York, 11219, United States
-
Masarykuv onkologicky ustav /ID# 232426
RECRUITINGBrno, 656 53, Czechia
-
Mayo Clinic - Rochester /ID# 252052
ACTIVE_NOT_RECRUITINGRochester, Minnesota, 55905-0001, United States
-
Mayo Clinic Arizona /ID# 255858
ACTIVE_NOT_RECRUITINGPhoenix, Arizona, 85054-4504, United States
-
Mayo Clinic Hospital Jacksonville /ID# 254688
COMPLETEDJacksonville, Florida, 32224, United States
-
Mbal Uni Hospital /ID# 273707
RECRUITINGPanagyurishte, Pazardzhik, 4500, Bulgaria
-
Medical Oncology Associates /ID# 247003
COMPLETEDSpokane, Washington, 99208, United States
-
Medical Park Seyhan Hastanesi /ID# 255637
RECRUITINGAdana, 01140, Turkey (Türkiye)
-
Medical University of South Carolina /ID# 251383
COMPLETEDCharleston, South Carolina, 29425, United States
-
Medizinische Universitaet Innsbruck /ID# 240981
RECRUITINGInnsbruck, Tyrol, 6020, Austria
-
Medizinische Universitaet Wien /ID# 230615
RECRUITINGVienna, State of Vienna, 1090, Austria
-
Memorial Ankara Hastanesi /ID# 234212
RECRUITINGÇankaya, Ankara, 06520, Turkey (Türkiye)
-
Memorial University Medical Center /ID# 264081
COMPLETEDSavannah, Georgia, 31404, United States
-
Metropolitan Hospital /ID# 232158
RECRUITINGPiraeus, Attica, 18547, Greece
-
Metropolitan Hospital /ID# 239170
RECRUITINGPiraeus, Attica, 18547, Greece
-
Miyagi Cancer Center /ID# 234198
RECRUITINGNatori-shi, Miyagi, 981-1293, Japan
-
NHO Mito Medical Center /ID# 241709
RECRUITINGHigashiibaraki-gun, Ibaraki, 311-3193, Japan
-
NHO Nagoya Medical Center /ID# 246306
RECRUITINGNagoya, Aichi-ken, 460-0001, Japan
-
NTT Medical Center Tokyo /ID# 241067
RECRUITINGShinagawa-ku, Tokyo, 141-8625, Japan
-
Nagaoka Red Cross Hospital /ID# 240714
RECRUITINGNagaoka-shi, Niigata, 940-2085, Japan
-
Nagoya University Hospital /ID# 239990
RECRUITINGNagoya, Aichi-ken, 466-8560, Japan
-
Nanjing Drum Tower Hospital /ID# 231791
RECRUITINGNanjing, Jiangsu, 210008, China
-
Nantong Tumor Hospital /ID# 232424
RECRUITINGNantong, Jiangsu, 226300, China
-
Narodowy Instytut Onkologii im. Marii Sklodowskiej-Curie Panstwowy Instytut Bada /ID# 262095
RECRUITINGWarsaw, Masovian Voivodeship, 02-781, Poland
-
National Cancer Center /ID# 260663
RECRUITINGGoyang-si, Gyeonggido, 10408, South Korea
-
National Cancer Center Hospital /ID# 251134
RECRUITINGChuo-ku, Tokyo, 104-0045, Japan
-
National Cancer Center Hospital East /ID# 233775
RECRUITINGKashiwa-shi, Chiba, 277-8577, Japan
-
National Hospital Organization Kyushu Medical Center /ID# 238533
RECRUITINGFukuoka, Fukuoka, 810-8563, Japan
-
National Hospital Organization Mie Chuo Medical Center /ID# 246659
RECRUITINGTsu, Mie-ken, 514-1101, Japan
-
National Hospital Organization Tokyo Medical Center /ID# 246581
RECRUITINGMeguro-ku, Tokyo, 152-8902, Japan
-
National Taiwan University Hospital - Hsinchu branch /ID# 238393
RECRUITINGHsinchu, 30059, Taiwan
-
National Taiwan University Hospital /ID# 238378
RECRUITINGTaipei, 100, Taiwan
-
Nebraska Hematology Oncology /ID# 257710
COMPLETEDLincoln, Nebraska, 68506, United States
-
Nemocnice AGEL Novy Jicin, a.s. /ID# 232427
COMPLETEDNový Jičín, 741 01, Czechia
-
Ningbo No. 2 Hospital /ID# 242478
RECRUITINGNingbo, Zhejiang, 315010, China
-
Northwell Health - Monter Cancer Center /ID# 247081
COMPLETEDLake Success, New York, 11042, United States
-
Nottingham City Hospital /ID# 254707
RECRUITINGNottingham, Nottinghamshire, NG5 1PB, United Kingdom
-
O.P.D. Hospital Civil de Guadalajara /ID# 238488
RECRUITINGGuadalajara, Jalisco, 44280, Mexico
-
OC Oncoclínicas SP /ID# 261828
RECRUITINGSão Paulo, São Paulo, 05874-230, Brazil
-
Ocala Oncology Florida Cancer Affiliates - Main /ID# 234228
COMPLETEDOcala, Florida, 34474-4445, United States
-
Odense University Hospital /ID# 241663
RECRUITINGOdense, Region Syddanmark, 5000, Denmark
-
Oncocenter - Oncologie Clinica Srl /Id# 239103
RECRUITINGTimișoara, Timiș County, 300166, Romania
-
Onvida Health Yuma Medical Center /ID# 253625
COMPLETEDYuma, Arizona, 85364, United States
-
Ordensklinikum Linz Elisabethinen /ID# 240967
RECRUITINGLinz, Upper Austria, 4010, Austria
-
Osaka Habikino Medical Center /ID# 239989
RECRUITINGHabikino-shi, Osaka, 583-8588, Japan
-
Osaka Metropolitan University Hospital /ID# 238895
RECRUITINGOsaka, Osaka, 545-8586, Japan
-
Peking Union Medical College Hospital East - Dongdan Campus /ID# 233175
RECRUITINGBeijing, Beijing Municipality, 100730, China
-
People's Hospital of Guizhou Province /ID# 243614
RECRUITINGGuiyang, Guizhou, 550002, China
-
People's Hospital of Henan Province /ID# 242187
RECRUITINGZhengzhou, Henan, 450003, China
-
Port Macquarie Base Hospital /ID# 273654
RECRUITINGPort Macquarie, New South Wales, 2444, Australia
-
Premiere Oncology Foundation /ID# 253954
COMPLETEDSanta Monica, California, 90404, United States
-
Pusan National University Yangsan Hospital /ID# 257836
RECRUITINGYangsan, Gyeongsangnam-do, 50612, South Korea
-
Renown Medical Group - Oncology/Hematology /ID# 247942
COMPLETEDReno, Nevada, 89502-1464, United States
-
Roskilde Sygehus /ID# 241842
RECRUITINGRoskilde, Region Sjælland, 4000, Denmark
-
S.C. Sigmedical Services SRL /ID# 239108
RECRUITINGSuceava, 720214, Romania
-
SC RTC Radiology Therapeutic Center SRL /ID# 240744
RECRUITINGOtopeni, Ilfov, 075100, Romania
-
SMG-SNU Boramae Medical Center /ID# 233710
RECRUITINGSeoul, Seoul Teugbyeolsi, 07061, South Korea
-
Sahlgrenska Universitetssjukhuset /ID# 229943
RECRUITINGGothenburg, Västra Götaland County, 413 46, Sweden
-
Saint Louis University Cancer Center /ID# 260722
COMPLETEDSt Louis, Missouri, 63110-2539, United States
-
Samsung Medical Center /ID# 256941
RECRUITINGSeoul, Seoul Teugbyeolsi, 06351, South Korea
-
San Juan Oncology Associates /ID# 244387
COMPLETEDFarmington, New Mexico, 87401, United States
-
Sandton Oncology Medical Group PTY Ltd /ID# 230843
COMPLETEDJohannesburg, Gauteng, 2196, South Africa
-
Sc Oncolab Srl /Id# 239105
RECRUITINGCraiova, Dolj, 200385, Romania
-
Sendai Kousei Hospital /ID# 253350
RECRUITINGSendai, Miyagi, 980-0873, Japan
-
Shandong Cancer Hospital /ID# 251506
RECRUITINGJinan, Shandong, 251601, China
-
Shanghai Chest Hospital /ID# 231897
RECRUITINGShanghai, Shanghai Municipality, 200030, China
-
Shanxi Cancer Hospital /ID# 258674
RECRUITINGTaiyuan, Shanxi, 030009, China
-
Sichuan Cancer Hospital /ID# 239707
RECRUITINGChengdu, Sichuan, 610041, China
-
Sociedad Oncovida /ID# 231152
COMPLETEDProvidencia, Santiago Metropolitan, 7510032, Chile
-
Sociedad Prosalud Montes y Orlandi /ID# 231154
RECRUITINGProvidencia, Santiago Metropolitan, 7500713, Chile
-
Sociedad de Oncologia y Hematologia del Cesar SAS /ID# 258130
RECRUITINGValledupar, Cesar Department, 200001, Colombia
-
Soroka University Medical Center /ID# 252711
RECRUITINGBeersheba, Southern District, 8410101, Israel
-
Spitalul Pelican /ID# 254066
RECRUITINGOradea, Bihor County, 410469, Romania
-
Springfield Clinic - First /ID# 262290
ACTIVE_NOT_RECRUITINGSpringfield, Illinois, 62702, United States
-
St Francis Cancer Center /ID# 243596
COMPLETEDGreenville, South Carolina, 29607-5253, United States
-
St. Luke's Hospital - Chesterfield /ID# 251688
COMPLETEDChesterfield, Missouri, 63017, United States
-
St. Lukes Hosp. of Kansas City /ID# 259940
RECRUITINGKansas City, Missouri, 64111, United States
-
Steve Biko Academic Hospital /ID# 230883
RECRUITINGPretoria, Gauteng, 0001, South Africa
-
Taipei Medical University Hospital /ID# 238380
RECRUITINGTaipei, 11031, Taiwan
-
Taizhou Hospital of Zhejiang Province /ID# 232021
RECRUITINGLinhai, Zhejiang, 317000, China
-
Takarazuka City Hospital /ID# 240786
RECRUITINGTakarazuka-shi, Hyōgo, 665-0827, Japan
-
Tel Aviv Sourasky Medical Center /ID# 260519
RECRUITINGTel Aviv, Tel Aviv, 6423906, Israel
-
The Affiliated Cancer Hospital of Xinjiang Medical University /ID# 240094
RECRUITINGÜrümqi, Xinjiang, 830000, China
-
The Affiliated Hospital of Inner Mongolia Medical University /ID# 242179
COMPLETEDHohhot, Inner Mongolia, 010050, China
-
The Catholic University Of Korea St. Vincent's Hospital /ID# 256942
RECRUITINGSuwon, Gyeonggido, 16247, South Korea
-
The Christie Hospital /ID# 243422
RECRUITINGManchester, M20 4BX, United Kingdom
-
The Edith Wolfson Medical Center /ID# 233781
COMPLETEDHolon, Southern District, 5822000, Israel
-
The First Affiliated Hospital Of Guangzhou Medical University /ID# 238591
RECRUITINGGuangzhou, Guangdong, 510163, China
-
The First Affiliated Hospital of Chongqing Medical University /ID# 251592
RECRUITINGChongqing, Chongqing Municipality, 400016, China
-
The First Affiliated Hospital of Nanchang University /ID# 231934
RECRUITINGNanchang, Jiangxi, 330006, China
-
The First Affiliated Hospital of Xi'an Jiaotong University /ID# 232023
RECRUITINGXi'an, Shaanxi, 710061, China
-
The First Affiliated Hospital of Xiamen University /ID# 242381
RECRUITINGXiamen, Fujian, 361003, China
-
The First Affiliated Hospital, Zhejiang University School of Medicine /ID# 232032
RECRUITINGHangzhou, Zhejiang, 310003, China
-
The First affiliated Hospital of Nanyang Medical College /ID# 244652
RECRUITINGNanyang, Henan, 473007, China
-
The Oncology Institute Of Hope & Innovation -East Los A /ID# 239774
COMPLETEDLos Angeles, California, 90033, United States
-
The Royal Marsden NHS Foundation Trust /ID# 246974
RECRUITINGLondon, SW3 6JJ, United Kingdom
-
The Second Affiliated Hospital of Dalian Medical University /ID# 239755
RECRUITINGDalian, Liaoning, 116023, China
-
The Second Affiliated Hospital of Nanchang University /ID# 231935
RECRUITINGNanchang, Jiangxi, 330008, China
-
Thoracic General Hospital of Athens I Sotiria /ID# 230824
RECRUITINGAthens, Attica, 11527, Greece
-
Thoraxklinik Heidelberg gGmbH /ID# 239656
RECRUITINGHeidelberg, Baden-Wurttemberg, 69126, Germany
-
Tianjin Cancer Hospital /ID# 233176
RECRUITINGTianjin, Tianjin Municipality, 300000, China
-
Tianjin Medical University General Hospital /ID# 231839
RECRUITINGTianjin, Tianjin Municipality, 300052, China
-
Tochigi Cancer Center /ID# 240020
RECRUITINGUtsunomiya, Tochigi, 320-0834, Japan
-
Tongji Hospital Tongji Medical College of HUST /ID# 239575
RECRUITINGWuhan, Hubei, 430030, China
-
Toyama University Hospital /ID# 241660
RECRUITINGToyama, Toyama, 930-0194, Japan
-
Trinity Health St. Joseph Mercy Ann Arbor /ID# 232190
COMPLETEDYpsilanti, Michigan, 48197-1051, United States
-
UCL Namur University Hospital, Site Sainte-Elisabeth /ID# 246769
RECRUITINGNamur, 5000, Belgium
-
UCLH NHS FT - University College Hospital /ID# 249407
RECRUITINGLondon, Greater London, NW1 2BU, United Kingdom
-
UMHAT Multiprofile Hospital for Active Treatment Sveta Marina /ID# 234112
RECRUITINGVarna, 9009, Bulgaria
-
UOMi Cancer Center - Clinica Tres Torres /ID# 240584
RECRUITINGBarcelona, 08017, Spain
-
UZ Gent /ID# 273244
RECRUITINGGhent, Oost-Vlaanderen, 9000, Belgium
-
Uludag University Medical Faculty /ID# 234205
RECRUITINGBursa, 16059, Turkey (Türkiye)
-
Unidade Local de Saude Sao Joao /ID# 241930
RECRUITINGPorto, 4200-319, Portugal
-
Union Hospital Tongji Medical College /ID# 231904
RECRUITINGWuhan, Hubei, 430048, China
-
Universitaetsklinikum Carl Gustav Carus Dresden /ID# 274719
RECRUITINGDresden, Saxony, 01307, Germany
-
Universitaetsklinikum Giessen /ID# 252973
RECRUITINGGiessen, Hesse, 35392, Germany
-
Universitaetsklinikum Hamburg-Eppendorf /ID# 239658
RECRUITINGHamburg, 20246, Germany
-
Universitaetsklinikum Jena /ID# 239661
RECRUITINGJena, Thuringia, 07747, Germany
-
Universitair Ziekenhuis Antwerpen /ID# 239971
RECRUITINGEdegem, Antwerpen, 2650, Belgium
-
Universitatsklinikum Mannheim /ID# 238331
RECRUITINGMannheim, Baden-Wurttemberg, 68167, Germany
-
University Hospitals Birmingham NHS Foundation Trust /ID# 258141
RECRUITINGBirmingham, B15 2TH, United Kingdom
-
University Multiprofile Hospital for Active Treatment Sofiamed /ID# 234108
RECRUITINGSofiya, Sofia, 1797, Bulgaria
-
University of Alabama at Birmingham - Main /ID# 247074
COMPLETEDBirmingham, Alabama, 35233, United States
-
University of Miyazaki Hospital /ID# 242161
RECRUITINGMiyazaki, Miyazaki, 889-1692, Japan
-
Valley Medical Center /ID# 253950
RECRUITINGRenton, Washington, 98055-5738, United States
-
Vitaz /Id# 246773
RECRUITINGSint-Niklaas, Oost-Vlaanderen, 9100, Belgium
-
Wakayama Medical University Hospital /ID# 234004
RECRUITINGWakayama, Wakayama, 641-8510, Japan
-
Warminsko-Mazurskie Centrum Chorob Pluc w Olsztynie /ID# 239025
RECRUITINGOlsztyn, Warmian-Masurian Voivodeship, 10-357, Poland
-
West China Hospital, Sichuan University /ID# 233703
RECRUITINGChengdu, Sichuan, 610041, China
-
Westmead Hospital /ID# 274447
RECRUITINGWestmead, New South Wales, 2145, Australia
-
Wielkopolskie Centrum Pulmonologii i Torakochirurgii im. Eugenii i Janusza Zeyla /ID# 262489
RECRUITINGPoznan, Greater Poland Voivodeship, 60-569, Poland
-
William Osler Health System - Brampton Civic Hospital /ID# 254420
RECRUITINGBrampton, Ontario, L6R 3J7, Canada
-
Wits Clinical Research /ID# 230841
COMPLETEDJohannesburg, Gauteng, 1864, South Africa
-
Yamagata University Hospital /ID# 240815
COMPLETEDYamagata, Yamagata, 990-9585, Japan
-
Yamaguchi - Ube Medical Center /ID# 258779
RECRUITINGUbe-shi, Yamaguchi, 755-0241, Japan
-
Yokohama City University Medical Center /ID# 246554
RECRUITINGYokohama, Kanagawa, 232-0024, Japan
-
Yunnan Cancer Hospital /ID# 251388
RECRUITINGKunming, Yunnan, 650118, China
-
ZIV Medical Center /ID# 238606
RECRUITINGSafed, Northern District, 13100, Israel
-
Zhejiang Cancer hospital /ID# 242476
RECRUITINGHangzhou, Zhejiang, 310022, China
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Ziekenhuis St. Jansdal /ID# 251932
RECRUITINGHarderwijk, Gelderland, 3844 DG, Netherlands
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