Can remote pilates help women with lipedema breathe easier?
NCT ID NCT06695403
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study compares two exercise approaches—supervised Pilates and telerehabilitation (remote Pilates)—to see which better improves exercise capacity and quality of life in women with lipedema. Participants will also follow a low-carb, high-fat diet for 12 weeks. The goal is to find effective, accessible ways to manage symptoms like pain and limited mobility.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Pilates exercise and telerehabilitation
- What this could lead to
- If successful, this could show that home-based telerehabilitation is as effective as supervised Pilates for improving exercise capacity and quality of life in women with lipedema.
- What could go wrong
- This is a small, early-stage study with 60 participants, so results may not apply to all people with lipedema. The diet component may also influence outcomes, making it hard to isolate the effect of exercise alone.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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60 people
The number who actually took part.
- Started
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Nov 2024
- Finished
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Mar 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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35 to 45 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: 1. Sixty female patients diagnosed with lipedema. 2. Their ages will range from 35-45 years old. 3. Patients diagnosed with lipedema ≥ 5 years. 4. Patients with grade 2 and 3 lipedema. 5. Patients with type 2 and 3 lipedema. 6. Patients with BMI ≥ 25 kg/m2 7. All patients will be clinically stable. Exclusion Criteria: Patient with any of the following will be excluded from the study: 1. Patients with lower limb edematous diseases such as lymphedema or chronic venous insufficiency. 2. Patients with history of previous liposuction. 3. Patients with asymmetrical lower limbs. 4. Patients with history of bariatric surgeries. 5. Patients on weight loss medications. 6. Patients any medical condition prohibiting exercise (cardiac pacemakers, diabetes mellitus, uncontrolled hypertension, and congestive heart failure) 7. Pregnant females. 8. Patients with BMI ≥ 40 kg/m2 (morbid obese). 9. Cancer patients (patients on chemotherapy, immunotherapy radiopathy). 10. Infectious diseases (HIV/AIDS, HCV, and Tuberculosis). 11. Chronic inflammatory autoimmune disease such as Sjogren's syndrome 12. Patients with neurological disorders: stroke and epilepsy.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Faculty of physical therapy
Cairo, Egypt, 3753450, Egypt
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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