New home rehab program aims to ease chemo brain and nerve damage
NCT ID NCT07159854
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study tests a home-based tele-rehabilitation program for people who have thinking and movement problems after chemotherapy. Sixty adults who finished chemo will be split into two groups: one gets 15 sessions of personalized cognitive and motor exercises via a tablet and remote systems, the other gets standard educational videos. The goal is to see if the program is easy to use and improves quality of life and daily function.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- tele-rehabilitation program (cognitive and motor exercises delivered via tablet and remote systems)
- What this could lead to
- If it works, this could offer a convenient, home-based way to manage chemotherapy-related thinking and movement problems, improving daily life for cancer survivors.
- What could go wrong
- This is a small, early-stage pilot study with only 60 participants, so results may not apply to everyone. The program requires consistent effort, and benefits may vary.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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About 60 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Sep 2025
An estimate. Start dates often move.
- Expected to finish
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Aug 2026
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult subjects (\>18 years old) with central and/or peripheral neurotoxic sequelae following a history of cancer treated with chemotherapeutic agents (Cisplatin and Taxanes), in accordance with the criteria of the International Cognitive Cancer Task Force (Wefel et al., 2011. 10.1016/S1470-2045(10)70294-1) * agreement to participate with the signature of the informed consent form; Exclusion Criteria: * Ongoing chemotherapy treatment; * Pre-existing neurological or psychiatric comorbidities (e.g., epilepsy, post-stroke disability, neurodegenerative diseases, genetically based polyneuropathy); * Severe visual or hearing impairments that could interfere with the use of technology; * Severe cognitive impairment (Mini-Mental State Examination score \<18); * Severe postural disability associated with a high risk of falling at home, as documented in the clinical evaluation; * Contraindications to undergoing MRI examination; * Ongoing rehabilitation treatment.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
Only the study team decides who joins. These are the ways to reach them.
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The places running it
1 site. The list below names each one and where it is.
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The official record
ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.
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A doctor treating you
A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.
Contacts and locations
Locations
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IRCCS Fondazione Don Carlo Gnocchi ONLUS
Milan, 20148, Italy