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New Two-Drug combo may beat standard Four-Drug regimen for stomach bug

NCT ID NCT05647278

First seen Jan 22, 2026 · Last updated May 20, 2026 · Updated 19 times

Summary

This study tested whether a simpler two-drug combination (tegoprazan and amoxicillin) works better than the standard four-drug treatment for eradicating H. pylori, a bacteria that can cause stomach ulcers. 370 adults with H. pylori infection participated. The goal was to see if the two-drug approach could achieve higher eradication rates with fewer side effects. Results will help doctors choose the best first-line treatment.

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Contacts and locations

Locations

  • Hangzhou first people's Hospital

    Hangzhou, Zhejiang, 310000, China

Conditions

Explore the condition pages connected to this study.