New drug teclistamab tested in patients with Hard-to-Treat myeloma
NCT ID NCT06062537
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study is tracking 200 adults with multiple myeloma whose cancer has returned or stopped responding to treatment. They are receiving teclistamab, a drug that helps the immune system find and destroy myeloma cells. Researchers are measuring how many patients respond to the drug and monitoring side effects in a real-world setting.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- teclistamab (a drug that helps the immune system attack cancer cells)
- What this could lead to
- If successful, this study could confirm that teclistamab works well and is safe for patients with multiple myeloma who have not responded to other treatments.
- What could go wrong
- This is an observational study, not a controlled trial, so results may be less definitive. Teclistamab can cause serious side effects like infections or immune reactions.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Participants
-
200 people
The number who actually took part.
- Started
-
Sep 2023
- Expected to finish
-
Dec 2026
An estimate. End dates often move.
- Lead sponsor
-
A research network
The lead sponsor is a research network or cooperative group.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
French adult patient relapsed and refractory multiple myeloma receving teclistamab
- Ages
-
18 years and older
- Sex
-
Anyone
- Healthy volunteers
-
Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Adult patient (≥18 years) with multiple myeloma who will receive at least one dose of teclistamab (first dose of the step-up dose) Exclusion Criteria: * Patients alive at the start of the study who did not receive study information or who objected to the collection of data * Patients who received teclistamab as part of an interventional clinical trial * Patients who are initiating teclistamab as part of a current interventional clinical trial
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for Multiple myeloma are added.
Genom att skicka in godkänner du våra Användarvillkor
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
-
CH Bretagne Atlantique
Vannes, France
-
CH Dunkerque
Dunkirk, France
-
CH Perpignan
Perpignan, France
-
CH d'ANNECY
Annecy, France
-
CH de METZ
Metz, France
-
CHU Amiens Picardie
Amiens, France
-
CHU Bordeaux
Bordeaux, 31400, France
-
CHU CAEN
Caen, France
-
CHU Clermont-Ferrand Site Estaing
Clermont-Ferrand, France
-
CHU Henri Mondor
Créteil, France
-
CHU Saint-Eloi - CHU de Montpellier
Montpellier, France
-
CHU Toulouse
Toulouse, France
-
CHU de Besançon
Besançon, France
-
CHU de Lille
Lille, France
-
CHU de Nice
Nice, France
-
CHU de Tours
Tours, France
-
Centre Henri Becquerel
Rouen, France
-
Centre hospitalier Métropole de Savoie
Chambéry, France
-
Centre hospitalier d'Argenteuil
Argenteuil, France
-
Centre hospitalier de Brive-la-Gaillarde
Brive-la-Gaillarde, France
-
Chu Dijon
Dijon, France
-
Chu de Nantes
Nantes, France
-
Chu de Rennes
Rennes, France
-
Groupe hospitalier Bretagne Sud
Lorient, France
-
Hopital Necker
Paris, France
-
Hopital Novo
Pontoise, France
-
Hopital de Hautepierre
Strasbourg, France
-
Hopital de la cote Basque
Bayonne, France
-
Hopital saint louis
Paris, France
-
Institut Paoli Calmette
Marseille, France
-
Institut de Cancérologie Lucien Neuwirth, CHU Saint-Etienne
Saint-Priest-en-Jarez, France
More trials for these conditions
Other studies related to the condition(s) this trial covers.
- Cheap blood count ratios eyed as window into Myeloma's inflammatory grip
- Can a t-cell engager rescue myeloma that outsmarted CAR-T?
- Can myeloma treatment work without steroids?
- Double-Drug attack on Hard-to-Treat lymphomas
- Banking blood and bone marrow to decode plasma cell disorders
- Which scan sees hidden myeloma better: PET or MRI?