Shock and stretch: new combo therapy targets migraine pain
NCT ID NCT05706077
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested whether a gentle brain stimulation technique (tDCS) combined with physical therapy can reduce pain in women with chronic migraine. 80 women aged 18-50 were split into four groups to compare the treatments alone or together. The goal was to see if these non-drug approaches could lessen pain intensity and improve quality of life.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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80 people
The number who actually took part.
- Started
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Mar 2023
- Finished
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Feb 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 50 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Women; * 18-50 years old; * with Chronic Migraine according to ICHD-3 beta; * literate; * stable on routine medications specific for MC for at least 2 months, who were not undergoing other types of non-pharmacological interventions for MC, not lactating or pregnant, without neurological diseases or serious neuropsychiatric diseases, without other types of associated headaches, without signs and/or symptoms of spinal radiculopathy, without metal implants located in the head and/or cochlear implants. Exclusion Criteria: * who perhaps become pregnant during the execution of the clinical trial * present some disease that disables their continuity in the treatment * start another type of treatment * show changes in physical activity and/or eating routine during the research * has severe depression (BDI \> 35).
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Federal University of Paraiba
João Pessoa, Paraíba, Brazil
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Other studies related to the condition(s) this trial covers.
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