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Could a head zapper ease tough pain syndrome?

NCT ID NCT07361692

Symptom relief Sponsor: Polyclinique de l'Europe Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tests whether a non-invasive brain stimulation technique called tDCS can reduce pain in people with Complex Regional Pain Syndrome (CRPS). Thirty-two adults with active CRPS will receive either real or sham stimulation over several sessions. The goal is to see if this safe, drug-free approach can offer meaningful pain relief.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcranial direct current stimulation (tDCS)
What this could lead to
If it works, this could offer a safe, drug-free option to reduce chronic pain in people with Complex Regional Pain Syndrome.
What could go wrong
This is a small, early-stage trial with only 32 people. The placebo effect is strong in pain studies, so results may not be conclusive or widely applicable.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 32 people

The number the study aims to enrol. It can still change while the study runs.

Started

Apr 2026

Expected to finish

Jun 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 years and older

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Major * Clinically active or active complex regional pain syndrome (CRPS) with positive Budapest criteria * Scintigraphy showing signs consistent with CRPS * Being affiliated with or a beneficiary of a social security scheme Exclusion Criteria: * Algodystrophy no longer meeting the Budapest criteria * Relative contraindication to tDCS: psychosis (including treated psychosis), uncontrolled epilepsy, large scalp scar, intracerebral/intracranial metallic body * Pregnant or breastfeeding women * Minors * Persons under legal protection (guardianship, conservatorship, and protective supervision) * Persons deprived of their liberty by judicial or administrative order * Unwilling individuals who cannot give their consent or cannot return for scheduled visits according to the protocol

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Conditions

The condition(s) this trial relates to.

anxiety disorder complex regional pain syndrome complex regional pain syndrome type 1 Pain

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Clinically active or active complex regional pain syndrome (CRPS) with positive budapest criteria Complex regional pain syndrome (CRPS) Scintigraphy showing signs consistent with CRPS

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Polyclinique de l'Europe

    RECRUITING

    Saint-Nazaire, 44600, France

More trials for these conditions

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