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Can a gentle brain zap help people with ataxia walk better?

NCT ID NCT07250321

First seen Jan 08, 2026 · Last updated Jun 19, 2026 · Updated 21 times

Summary

This study tests whether a non-invasive brain stimulation technique called transcranial direct current stimulation (tDCS) can improve movement in people with degenerative ataxia, a rare condition that damages the cerebellum and impairs balance and coordination. Sixteen participants will receive either real or sham stimulation, and researchers will measure changes using clinical scales and precise motion analysis. The goal is to see if tDCS can offer a safe, drug-free way to ease symptoms.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • University of Cagliari

    Cagliari, 09100, Italy

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

transcranial direct current stimulation (tDCS)

What this could lead to

If it works, this could point toward a non-invasive way to ease movement problems in people with degenerative ataxia, improving balance and coordination.

What could go wrong

This is a very small early-stage trial (16 people) with mixed prior results. The effect may be small or not last, and not everyone may benefit.

Conditions

The condition(s) this trial relates to.

Ataxia autosomal dominant cerebellar ataxia cerebellar ataxia hereditary ataxia spinocerebellar ataxia 9 Spinocerebellar Ataxias Spinocerebellar Degenerations

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.