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Brain stimulation before computer training may sharpen memory and focus in schizophrenia

NCT ID NCT07273175

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only This study
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether a mild electrical current applied to the scalp (tDCS) before computer-based cognitive training can improve thinking skills like memory and attention in people with schizophrenia. 120 adults aged 18-65 will receive either real or fake tDCS for 20 minutes, followed by 30 minutes of brain games, over 15 sessions in three weeks. Researchers will compare test scores and brain activity at the start, right after treatment, and 8 weeks later to see if the effects last.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
transcranial direct current stimulation (tDCS)
What this could lead to
If it works, this could point toward a way to boost cognitive rehabilitation for people with schizophrenia, potentially improving memory, attention, and planning.
What could go wrong
This is an early-stage study with 120 people, so results may not apply to everyone. The improvement might be small or not last long, and tDCS can cause mild side effects like tingling or headache.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 120 people

The number the study aims to enrol. It can still change while the study runs.

Started

Oct 2023

Expected to finish

Dec 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 65 years

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: 1. Adults aged 18-65 years with schizophrenia diagnosed according to DSM-5 criteria (Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition) 2. Ability to provide informed consent for tDCS treatment and use of collected data for research purposes 3. Mentally stable, may receive pharmacological treatment Exclusion Criteria: 1. Contraindications to tDCS, including: Implanted electronic devices Metal implants in the head History of seizures Contact allergy to materials used for tDCS stimulation (electrodes) 2. Pregnancy 3. Head injury with loss of consciousness or neurosurgery performed within the previous six months 4. History of stroke, aneurysm, brain tumor, or other conditions causing increased intracranial pressure 5. Migraines 6. Substance abuse 7. Currently receiving electroconvulsive therapy (ECT) Withdrawal criteria: participation will be discontinued if any of the following occur: Urgent medical issues Serious adverse events or side effects Participant unwillingness to continue in the trial

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

How to take part

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  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    The full official record for this study. This one lists no contact details, but it is the first place any would appear.

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  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • Department of Old Age Psychiatry and Psychotic Disorders

    Lodz, Łódź Voivodeship, 92-216, Poland

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