Brain zapping study reveals how we process criticism
NCT ID NCT07406464
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at how a gentle electrical current applied to the brain (tDCS) changes the way healthy women process social criticism. 47 volunteers underwent brain scans while hearing critical, neutral, or praising comments. The goal was to understand brain activity and mood changes, not to treat any disease.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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47 people
The number who actually took part.
- Started
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Jul 2013
- Finished
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Mar 2014
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 35 years
- Sex
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Female participants only
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Female participants aged 18-35 years. * Right-handed, healthy volunteers. * No current or past psychiatric or neurological disorder as assessed by structured clinical interview (M.I.N.I.). * MRI-compatible (no metal implants, pacemaker, or contraindications for MRI scanning). * Not taking psychotropic medication. * Fluent in Dutch. * Provided written informed consent. Exclusion Criteria: * Current or past major depressive episode or any other psychiatric disorder. * History of epilepsy or seizures in participant * History of neurological illness or neurosurgical intervention. * Pregnancy. * Claustrophobia or inability to tolerate MRI environment. * Metal implants or other MRI-incompatible devices. * Skin lesions or dermatological conditions at electrode sites. * Unstable medical condition. * Use of medication that could influence brain activity or mood.
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As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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UZ Gent
Ghent, Oost-Vlaanderen, 9000, Belgium
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