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Supercharged immune cells take on HPV cancers

NCT ID NCT02858310

First seen Nov 01, 2025 · Last updated Apr 30, 2026 · Updated 25 times

Summary

This study tested a new treatment for cancers caused by HPV-16, like cervical and throat cancers. Researchers took participants' white blood cells, added genes to help them target a protein called E7 found in HPV cancer cells, and infused the modified cells back. The goal was to find a safe dose and see if the treatment could shrink tumors. 224 adults with advanced HPV-16 cancers took part.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • National Institutes of Health Clinical Center

    Bethesda, Maryland, 20892, United States

  • Rutgers Cancer Institute of New Jersey

    New Brunswick, New Jersey, 08901, United States

Conditions

Explore the condition pages connected to this study.