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New hope for kidney transplant patients: safer rejection prevention?

NCT ID NCT06365437

First seen Mar 16, 2026 · Last updated Jun 19, 2026 · Updated 17 times

Summary

This study tested a new drug called TCD601 (siplizumab) in 33 kidney transplant patients to see if it could safely prevent organ rejection. The drug was compared to a standard treatment (ATG). The trial was stopped early, so we have limited information, but the goal was to find a gentler option for transplant recipients.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Hospital Clinic de Barcelona

    Barcelona, 08036, Spain

  • Hospital Universitari de Bellvitge

    Barcelona, 08907, Spain

  • Innsbruck Medical University

    Innsbruck, A-6020, Austria

  • Karolinska University Hospital

    Stockholm, Huddinge, 14157, Sweden

  • Sahlgrenska University Hospital

    Gothenburg, 41345, Sweden

  • Skåne University Hospital

    Malmö, 20502, Sweden

  • University of Vienna

    Vienna, 1090, Austria

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

TCD601 (siplizumab)

What this could lead to

If it works, this could point toward a safer way to prevent organ rejection after kidney transplant, reducing side effects compared to current treatments.

What could go wrong

This is an early, small Phase 2 trial that was terminated, so results are limited. The drug may not prove safer or more effective than standard therapy, and risks include infection and rejection.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.