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New TB prevention pack tested in thousands of thai households

NCT ID NCT05581212

Prevention Sponsor: Institut de Recherche pour le Developpement Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This completed study tested a new public health pack to find and prevent tuberculosis (TB) early in people living with someone who has TB. Over 7,400 participants in Thailand were involved. The pack included active screening, treatment for active TB, and preventive therapy for those without active TB. The goal was to see if this approach could get more people started on preventive treatment quickly.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Tuberculosis Case-Finding, Treatment and Prevention Public Health Pack
What this could lead to
If successful, this approach could help reduce tuberculosis spread and improve preventive treatment uptake in high-risk households.
What could go wrong
This is a completed implementation study, so results are already known. The strategy may not be easily adopted in other regions or countries with different healthcare systems.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

7,455 people

The number who actually took part.

Started

May 2024

Finished

Jan 2026

Lead sponsor

A government agency

The lead sponsor is a government body.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Inclusion of the index cases * Age ≥18 years * Newly bacteriologically confirmed TB case (within 1 month of diagnosis) * Living in the same household for the last 3 months * Reporting at least one HH contact * Providing written informed consent for participation in the study Inclusion of contacts * All contacts living in the same HH, defined as any person who shared the same enclosed living space as the index TB case for one or more nights or for frequent or extended daytime periods for at least one month before the TB diagnosis is made. * Providing written informed consent (signed by adult (≥18 years) contacts; or by parents/guardians for minors \< 13 years or incapacitated people; written assent for children ≥13 years and \< 18 years). Exclusion Criteria: Exclusion of index cases * Index case who do not live in the catchment area of the study cluster * Index cases diagnosed with rifampicin resistance, multidrug resistance (MDR) or extensively drug-resistant (XDR-TB) * Index cases who are incarcerated Exclusion of the contacts \- contact currently on TPT or on TB treatment or who finished such treatment in the last 3 months.

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Conditions

The condition(s) this trial relates to.

tuberculosis

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Tuberculosis

Contacts and locations

Locations

  • Bang Lamung H.

    Bang Lamung, Thailand

  • Buriram H.

    Nakhon Ratchasima, Thailand

  • Chiangrai Prachanukroh H.

    Chiang Rai, Thailand

  • Chon Buri H.

    Chon Buri, Thailand

  • Hat Yai H.

    Songkhla, Thailand

  • Kalasin H.

    Kalasin, Thailand

  • Khon Kaen H.

    Khon Kaen, Thailand

  • Lampang H.

    Lampang, Thailand

  • Maharaj Nakhon Si Thammarat H.

    Nakhon Si Thammarat, Thailand

  • Nakornping H.

    Chiang Mai, Thailand

  • Phra Nakhon Si Ayutthaya H.

    Phra Nakhon Si Ayutthaya, Thailand

  • Ratchaburi H.

    Ratchaburi, Thailand

  • Samut Prakan H.

    Mueang Samut Prakan, Thailand

  • Samut Sakhon H.

    Samut Sakhon, Thailand

  • Si Sa Ket H.

    Si Sa Ket, Thailand

  • Songkhla H.

    Songkhla, Thailand

  • Sunpasitthiprasong H.

    Ubon Ratchathani, Thailand

  • Surat Thani H.

    Surat Thani, Thailand

  • Surin H.

    Nakhon Ratchasima, Thailand

  • Trang H.

    Trang, Thailand

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