New heart valve showdown: simpler procedure could change aortic stenosis care

NCT ID NCT05036018

Ongoing Disease control Sponsor: Leipzig Heart Science gGmbH Source: ClinicalTrials.gov ↗

First seen Feb 17, 2026 · Last updated May 21, 2026 · Updated 13 times

Summary

This study tests two newer self-expanding heart valves and a less invasive approach for replacing a narrowed aortic valve. About 836 people with severe aortic stenosis will be randomly assigned to receive one of the new valves or standard care, and also to a minimalist procedure or usual care. The goal is to see if these newer options reduce death, stroke, and other complications within 30 days.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

Get updates

Get notified about this study

Sign up to get updates when this study changes or when new studies for AORTIC VALVE STENOSIS are added.

Vår säkerhetsrekommendation!

Genom att skicka in godkänner du våra Användarvillkor

Contacts and locations

Show contact details

Locations

Heart Center Leipzig at University of Leipzig, Department of Internal Medicine/Cardiology

Leipzig, 04289, Germany
Helios Klinikum Wuppertal

Wuppertal, 42283, Germany
Herz- und Diabeteszentrum NRW

Bad Oeynhausen, 32545, Germany
Herzzentrum München

München, 80636, Germany
LMU Klinikum München

München, 81377, Germany
St.-Johannes-Hospital Dortmund

Dortmund, 44137, Germany
Universitätsklinikum Gießen

Giessen, 35392, Germany
Universitätsklinikum Köln

Cologne, 50937, Germany
Universitätsklinikum Tübingen

Tübingen, 72076, Germany
Zentralklinik Bad Berka

Bad Berka, 99437, Germany

Conditions

Explore the condition pages connected to this study.

AORTIC VALVE STENOSIS