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New combo therapy shows promise for Hard-to-Treat breast cancer

NCT ID NCT02390427

First seen Apr 11, 2026 · Last updated May 24, 2026 · Updated 7 times

Summary

This study tested a new drug called taselisib, which blocks a protein that helps cancer grow, combined with standard HER2-targeted therapies in 68 people with advanced HER2+ breast cancer. The main goal was to find the safest dose for future studies. Researchers also looked at whether the combination could shrink tumors or slow the disease.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Dana Farber Cancer Institute

    Boston, Massachusetts, 02215, United States

  • Massachusetts General Hospital

    Boston, Massachusetts, 02114, United States

  • Sarah Cannon Research Institute

    Nashville, Tennessee, 37203, United States

Conditions

Explore the condition pages connected to this study.