Experimental FGFR drug fails to reach goal in metastatic breast cancer trial
NCT ID NCT04024436
First seen Nov 13, 2025 · Last updated May 19, 2026 · Updated 20 times
Summary
This study tested a drug called futibatinib (TAS-120) in people with advanced breast cancer that has spread and has specific FGFR gene changes. The drug was given alone or with hormone therapy. The trial was stopped early, and results were not fully reported. It involved 64 adults who had already tried other treatments.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Locations
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AOU Modena Policlinico
Modena, Italy
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AOU Policlinico - Vittorio Emanuele
Catania, 95123, Italy
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Azienda Ospedaliero Universitaria Pisana
Pisa, 56126, Italy
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BIDMC
Boston, Massachusetts, 02115, United States
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Centre Leon Berard
Lyon, 69008, France
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Centro Hospitalar Universitario Lisboa Norte
Lisbon, 1649-035, Portugal
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Dana Farber Cancer Institute
Boston, Massachusetts, 02115, United States
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Florida Cancer Specialists
Fort Myers, Florida, 33901, United States
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Florida Cancer Specialists
St. Petersburg, Florida, 33705, United States
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Florida Cancer Specialists
Tallahassee, Florida, 32308, United States
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Florida Cancer Specialists
West Palm Beach, Florida, 33401, United States
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Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Roma, 00168, Italy
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HCA Healthcare UK
London, England, W1G 6AD, United Kingdom
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HCA Midwest Health
Kansas City, Missouri, 64132, United States
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Institut Gustave Roussy
Villejuif, Cedex, 94805, France
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Instituto Portugues de Oncologia do Porto
Porto, 4200-072, Portugal
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Istituto Europeo Di Oncologia - IEO
Milan, 20141, Italy
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Istituto Nazionale Tumori Regina Elena
Roma, 00144, Italy
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MD Anderson
Houston, Texas, 77030, United States
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Massachusetts General Hospital
Boston, Massachusetts, 02114, United States
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Mayo Clinic - AZ
Phoenix, Arizona, 85054, United States
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Mayo Clinic - FL
Jacksonville, Florida, 32224, United States
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Mayo Clinic - MN
Rochester, Minnesota, 55905, United States
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Moffitt Cancer Center
Tampa, Florida, 33612, United States
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Ospedale E. Agnelli
Pinerolo, 10064, Italy
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Porto University
Porto, 4099-001, Portugal
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START Madrid - CIOCC
Madrid, 28050, Spain
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SunnyBrook Health Sciences
Toronto, M4N 3M5, Canada
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Tennessee Oncology
Chattanooga, Tennessee, 37404, United States
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Tennessee Oncology
Nashville, Tennessee, 37203, United States
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The Christie NHS Foundation Trust
Manchester, England, M20 4BX, United Kingdom
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The Royal Marsden NHS Foundation Trust
Sutton, England, SM2 5PT, United Kingdom
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Tom Baker Cancer Center
Calgary, T2N 4N2, Canada
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USCF
San Francisco, California, 94115, United States
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UT Southwestern
Dallas, Texas, 75390, United States
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University Gregorio Marañon
Madrid, 28007, Spain
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Vall d'Hebron
Barcelona, 08035, Spain
Conditions
Explore the condition pages connected to this study.