Promising lung cancer combo aims to extend life in Late-Stage trial
NCT ID NCT06211036
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This phase 3 trial tests whether adding tarlatamab to durvalumab helps people with extensive-stage small-cell lung cancer live longer than durvalumab alone. About 563 participants who have already completed initial chemotherapy plus durvalumab will be randomly assigned to one of the two treatments. The main goal is to compare overall survival between the groups.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- tarlatamab and durvalumab
- What this could lead to
- If successful, this combination could offer a new, more effective treatment option for people with advanced small-cell lung cancer, potentially extending survival.
- What could go wrong
- This is a large phase 3 trial, but the combination may not prove better than durvalumab alone. Side effects from adding tarlatamab could be significant, and results may not apply to all patients.
This is an AI summary of the original study and may miss details. Read our disclaimer.
Study facts
What this study's own registry entry says, in plain language.
- Phase
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Phase 3
Large-scale testing in a bigger group. Usually the last step before a treatment can be approved.
- Participants
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563 people
The number who actually took part.
- Started
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Jun 2024
- Expected to finish
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Sep 2028
An estimate. End dates often move.
- Lead sponsor
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A company
The lead sponsor is a pharmaceutical, biotech, or medical-device company.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 99 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion: * Participant has provided informed consent prior to initiation of any study specific activities/procedures. * Age \>= 18 years (or \>= legal adult age within the country if it is older than 18 years). * Completed 3-4 cycles of platinum-etoposide chemotherapy with concurrent durvalumab as first-line treatment of extensive-stage (ES)-SCLC prior to enrollment, without disease progression (ongoing response or stable disease) per Response Evaluation Criteria in Solid Tumors Version 1.1 (RECIST 1.1). * Eastern Cooperative Oncology Group (ECOG) performance status (PS) of 0 to 1. * Minimum life expectancy \> 12 weeks. * Toxicities attributed to prior anti-cancer therapy resolved to grade ≤ 1, unless otherwise specified, excluding alopecia or fatigue. * Adequate organ function. * Histologically or cytologically documented extensive-stage disease (American Joint Committee on Cancer, 2017, IV small-cell lung cancer (SCLC) \[T any, N any, M1 a/b/c\]), or T3 to T4 due to multiple lung nodules that are too extensive or have tumor/nodal volume that is too large to be encompassed in a tolerable radiation plan. Participants with prior limited-stage (LS)-SCLC are allowed if the interval is \> 6 months since the end of previous therapy and progression, in discussion with the medical monitor. Exclusion * Symptomatic central nervous system (CNS) metastases, or leptomeningeal disease. Participants with treated brain metastases are eligible as per protocol. * Prior history of severe or life-threatening events from any immune-mediated therapy. * History of other malignancy within the past 2 years, with some exceptions as per protocol. * Active or prior documented autoimmune or inflammatory disorders as per protocol. * Myocardial infarction and/or symptomatic congestive heart failure (New York Heart Association \> class II) within 6 months of first dose of study treatment. * History of arterial thrombosis (e.g., stroke or transient ischemic attack) within 6 months of first dose of study treatment. * Evidence of interstitial lung disease (ILD) or active, non-infectious pneumonitis. * History of solid organ transplant. * Major surgical procedures within 28 days of first dose of study treatment. * Known human immunodeficiency virus (HIV) infection (participants with HIV infection on antiviral therapy and undetectable viral load are permitted with a requirement for regular monitoring for reactivation for the duration of treatment on study), hepatitis C infection (participants with hepatitis C that achieve a sustained virologic response after antiviral therapy are allowed), or hepatitis B infection (participants with hepatitis B surface antigen \[HBsAg\] or core antibody that achieve sustained virologic response with antiviral therapy are permitted with a requirement for regular monitoring for reactivation for the duration of treatment on the study). * Receiving systemic corticosteroid therapy or any other form of immunosuppressive therapy within 14 days prior to first dose of study treatment. * History of allergic reactions or acute hypersensitivity reaction to antibody therapies, platinum chemotherapy, or etoposide. * Participant with symptoms and/or clinical signs and/or radiographic signs that indicate an acute and/or uncontrolled active systemic infection within 7 days prior to the first dose of study treatment. * Participant has known active infection requiring parenteral antibiotic treatment. Upon completion of parenteral antibiotics and resolution of symptoms, the participant may be considered eligible for the study from an infection standpoint. * Treatment with live virus, including live-attenuated vaccination, within 4 weeks prior to the first dose of study treatment. Inactive vaccines (e.g., non-live or non-replicating agent) and live viral non-replicating vaccines (e.g., Jynneos for Monkeypox infection) within 30 days prior to first dose of study treatment. * Prior therapy with any selective inhibitor of the delta-like ligand 3 (DLL3) pathway. * Receiving another anti-cancer therapy. Adjuvant hormonal therapy for resected breast cancer is permitted. * Treatment in an alternative investigational trial within 28 days prior to enrollment. * Has received or is planning to receive consolidative chest radiation for extensive stage disease. * Female participants of childbearing potential unwilling to use protocol specified method of contraception during treatment as per protocol. * Female participants who are breastfeeding or who plan to breastfeed while on study as per protocol. * Female participants planning to become pregnant or donate eggs while on study as per protocol. * Female participants of childbearing potential with a positive pregnancy test assessed at screening by a highly sensitive serum pregnancy test. * Male participants with a female partner of childbearing potential who are unwilling to practice sexual abstinence (refrain from heterosexual intercourse) or use contraception during treatment as per protocol. * Male participants with a pregnant partner who are unwilling to practice abstinence or use a condom during treatment as per protocol. * Male participants unwilling to abstain from donating sperm during treatment as per protocol. * Participant has known sensitivity to any of the products or components to be administered during dosing. * Participant has known sensitivity to any of the products or components to be administered during dosing. * History or evidence of any other clinically significant disorder, condition or disease that, in the opinion of the investigator or physician if consulted, would pose a risk to participant safety or interfere with the study evaluation, procedures, or completion. * Participant likely to not be available to complete all protocol-required study visits or procedures, and/or to comply with all required study procedures (eg, Clinical Outcome Assessments) to the best of the participant and investigator's knowledge. Participants who are unable to complete clinical outcome assessments are eligible.
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Get notified about this study
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Affiliated Cancer Hospital of Xinjiang Medical University
Ürümqi, Xinjiang, 830054, China
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Affiliated Hospital of Guilin Medical University
Guilin, Guangxi, 541001, China
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Aichi Cancer Center
Nagoya, Aichi-ken, 464-8681, Japan
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Algemeen Ziekenhuis Maria Middelares
Ghent, 9000, Belgium
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Allegheny Health Network
Pittsburgh, Pennsylvania, 15212, United States
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Allina Health System dba Allina Health Cancer Institute
Saint Paul, Minnesota, 55102, United States
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Ankara Bilkent Sehir Hastanesi
Ankara, 06800, Turkey (Türkiye)
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Asan Medical Center
Seoul, 05505, South Korea
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Asklepios Fachkliniken Muenchen Gauting
Gauting, 82130, Germany
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Astera Cancer Care
East Brunswick, New Jersey, 08816, United States
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Attikon University Hospital
Athens, 12462, Greece
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Azienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda
Milan, 20162, Italy
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Azorg Campus Aalst - Moorselbaan
Aalst, 9300, Belgium
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Bagcilar Medipol Mega Universite Hastanesi
Istanbul, 34214, Turkey (Türkiye)
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Baptist Cancer Center Memphis Thoracic
Memphis, Tennessee, 38120, United States
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Beaumont Hospital
Dublin, 9, Ireland
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Beijing Cancer Hospital
Beijing, Beijing Municipality, 100142, China
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Beijing Cancer Hospital
Beijing, 100142, China
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Beijing Chaoyang Hospital, Capital Medical University
Beijing, Beijing Municipality, 100020, China
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CHU de Quebec Hopital de l Enfant Jesus
Québec, Quebec, G1R 2J6, Canada
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Cancer Research South Australia
Adelaide, South Australia, 5000, Australia
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Cancer and Hematology Centers of Western Michigan
Grand Rapids, Michigan, 49503, United States
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Cangzhou Peoples Hospital
Cangzhou, Hebei, 061011, China
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Cenantron Centro Avançado de Tratamento Oncologico Ltda
Belo Horizonte, Minas Gerais, 30130-090, Brazil
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Centre Hospitalier - Le Mans
Le Mans, 72000, France
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Centre Hospitalier Intercommunal de Creteil
Créteil, 94010, France
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Centre Hospitalier Regional Universitaire de Brest - Hopital Morvan
Brest, 29200, France
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Centre Hospitalier Universitaire Nord
Marseille, 13915, France
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Centre Hospitalier Universitaire de Nantes - Hopital Nord Laennec
Saint-Herblain, 44800, France
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Centre Hospitalier Universitaire de Strasbourg - Nouvel Hopital Civil
Strasbourg, 67091, France
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Centre Hospitalier Universitaire de Toulouse - Hopital Larrey
Toulouse, 31059, France
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Centre Hospitalier Universitaire-Universite Catholique de Louvain Namur-Site Godinne
Yvoir, 5530, Belgium
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Centre Leon Berard
Lyon, 69008, France
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Centres Hospitaliers Universitaires - Helora - Hopital de Mons - Site Kennedy
Mons, 7000, Belgium
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Centro Ricerche Cliniche Di Verona Societa responsabilita limitata
Verona, 37126, Italy
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Chris OBrien Lifehouse
Camperdown, New South Wales, 2050, Australia
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Chungbuk National University Hospital
Cheongju Chungbuk, 28644, South Korea
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Clinica Universidad de Navarra
Pamplona, Navarre, 31008, Spain
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Clinique Teissier
Valenciennes, 59300, France
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Dana-Farber Cancer Institute
Boston, Massachusetts, 02215, United States
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Dolnoslaskie Centrum Onkologii, Pulmonologii i Hematologii
Wroclaw, 53-439, Poland
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Duke University
Durham, North Carolina, 27710, United States
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Emory University
Atlanta, Georgia, 30322, United States
-
Erasmus Medisch Centrum
Rotterdam, 3015 GD, Netherlands
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European Interbalkan Medical Center
Thessaloniki, 57001, Greece
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Exelsus Oncologia Clinica
San Miguel de Tucumán, Tucumán Province, 4000, Argentina
-
Fakultni nemocnice Brno
Brno, 625 00, Czechia
-
Fakultni nemocnice Olomouc
Olomouc, 779 00, Czechia
-
Fakultni nemocnice v Motole
Prague, 150 06, Czechia
-
Fejer Varmegyei Szent Gyorgy Egyetemi Oktato Korhaz
Székesfehérvár, 8000, Hungary
-
Franciscan Health Indianapolis
Indianapolis, Indiana, 46237, United States
-
Fujian Cancer Hospital
Fuzhou, Fujian, 350014, China
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Fundacao Antonio Prudente AC Camargo Cancer Center
São Paulo, São Paulo, 01509-900, Brazil
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Fundacion Centro Oncológico Riojano Integral para la Investigación y Prevención del Cáncer
La Rioja, F5300COE, Argentina
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Fundacion Medica de Rio Negro y Neuquen
Cipolletti, Río Negro Province, 8324, Argentina
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Greenslopes Private Hospital
Greenslopes, Queensland, 4120, Australia
-
Guangxi Medical University Affiliated Tumor Hospital
Nanning, Guangxi, 530201, China
-
Gyor-Moson-Sopron Varmegyei Petz Aladar Egyetemi Oktatokorhaz
Győr, 9024, Hungary
-
Health Pharma Professional Research SA de CV
Mexico City, Mexico City, 03100, Mexico
-
Henan Cancer Hospital
Zhengzhou, Henan, 450003, China
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Henry Dunant Hospital Center
Athens, 11526, Greece
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Hopital Cochin
Paris, 75014, France
-
Hospital Britanico de Buenos Aires
CABA, Buenos Aires, C1280AEB, Argentina
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Hospital Clinic i Provincial de Barcelona
Barcelona, Catalonia, 08036, Spain
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Hospital Cuf Descobertas
Lisbon, 1998-018, Portugal
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Hospital Cuf porto
Porto, 4100-180, Portugal
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Hospital Israelita Albert Einstein
São Paulo, São Paulo, 05652-900, Brazil
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Hospital Regional Universitario de Malaga
Málaga, Andalusia, 29011, Spain
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Hospital Sao Rafael-Idor
Salvador, Estado de Bahia, 40170-110, Brazil
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Hospital Universitari Vall d Hebron
Barcelona, Catalonia, 08035, Spain
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Hospital Universitari i Politecnic La Fe
Valencia, Valencia, 46026, Spain
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Hospital Universitario Ramon y Cajal
Madrid, 28034, Spain
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Hospital Universitario Virgen Macarena
Seville, Andalusia, 41009, Spain
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Hospital Uopeccan
Cascavel, Paraná, 85806-300, Brazil
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Hospital da Luz, SA
Lisbon, 1500-650, Portugal
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Hospital de Clinicas de Ijui
Ijuí, Rio Grande do Sul, 98700-000, Brazil
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Hospital de Clinicas de Passo Fundo
Passo Fundo, Rio Grande do Sul, 99010-260, Brazil
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Hospital de la Santa Creu i Sant Pau
Barcelona, Catalonia, 08041, Spain
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Hubei Cancer Hospital
Wuhan, Hubei, 430070, China
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Hyogo Cancer Center
Akashi-shi, Hyōgo, 673-8558, Japan
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IRCCS Istituto Oncologico Europeo
Milan, 20141, Italy
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IRCCS Istituto Tumori Giovanni Paolo II
Bari, 70124, Italy
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Infirmary Cancer Center
Mobile, Alabama, 36607, United States
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Inselspital Bern
Bern, 3010, Switzerland
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Institut Bergonie
Bordeaux, 33000, France
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Institut Catala d Oncologia Hospitalet Hospital Duran i Reynals
L'Hospitalet de Llobregat, Catalonia, 08908, Spain
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Institut Jules Bordet
Brussels, B-1070, Belgium
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Institut regional du Cancer Montpellier
Montpellier, 34298, France
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Instituto Alexander Fleming
Capital Federal, Buenos Aires, C1426ANZ, Argentina
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Institutul Oncologic Prof Dr Ion Chiricuta Cluj-Napoca
Cluj-Napoca, 400015, Romania
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Instytut Gruzlicy i Chorob Pluc
Warsaw, 01-138, Poland
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Irmandade da Santa Casa de Misericordia de Porto Alegre
Porto Alegre, Rio Grande do Sul, 90020-090, Brazil
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Izmir Katip Celebi Universitesi Ataturk Egitim ve Arastirma Hastanesi
Izmir, 35150, Turkey (Türkiye)
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Jiamusi Cancer Hospital
Jiamusi, Heilongjiang, 154007, China
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Jiangxi Cancer hospital
Nanchang, Jiangxi, 330029, China
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Jilin Cancer Hospital
Changchun, Jilin, 130012, China
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Juntendo University Hospital
Bunkyo-ku, Tokyo, 113-8431, Japan
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Kanagawa Prefectural Hospital Organization Kanagawa Cancer Center
Yokohama, Kanagawa, 241-8515, Japan
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Kansai Medical University Hospital
Hirakata-shi, Osaka, 573-1191, Japan
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Kantonsspital Sankt Gallen
Sankt Gallen, 9007, Switzerland
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Kaohsiung Chang Gung Memorial Hospital
Kaohsiung City, 83301, Taiwan
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Kindai University Hospital
Osakasayama-shi, Osaka, 589-8511, Japan
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Kliniken der Stadt Koeln gGmbH
Cologne, 51109, Germany
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Kurume University Hospital
Kurume-shi, Fukuoka, 830-0011, Japan
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Kyushu University Hospital
Fukuoka, Fukuoka, 812-8582, Japan
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Landeskrankenhaus Feldkirch
Rankweil, 6830, Austria
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Linyi Cancer Hospital
Linyi, Shandong, 276000, China
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London Health Sciences Centre
London, Ontario, N6A 5W9, Canada
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LungenClinic Grosshansdorf GmbH
Großhansdorf, 22927, Germany
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Maastricht Universitair Medisch Centrum
Maastricht, 6229 HX, Netherlands
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Matrai Gyogyintezet
Gyöngyös, 3200, Hungary
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Mayo Clinic
Rochester, Minnesota, 55905, United States
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Medical Park Seyhan Hastanesi
Mersin, 33200, Turkey (Türkiye)
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Medical University of South Carolina
Charleston, South Carolina, 29425, United States
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Medizinische Universitaet Graz
Graz, 8036, Austria
-
Meir Medical Center
Kfar Saba, 4428164, Israel
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Metropolitan General
Athens, 15562, Greece
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Metropolitan Hospital
Athens, 18547, Greece
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Monash Medical Centre
Clayton, Victoria, 3168, Australia
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Montefiore Medical Center - Bronx
The Bronx, New York, 10461, United States
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Nanjing Chest Hospital
Nanjing, Jiangsu, 210029, China
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National Cancer Center
Goyang-si Gyeonggi-do, 10408, South Korea
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National Cancer Center Hospital
Chuo-ku, Tokyo, 104-0045, Japan
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National Cancer Center Hospital East
Kashiwa-shi, Chiba, 277-8577, Japan
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National Cheng Kung University Hospital
Tainan, 70403, Taiwan
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National Hospital Organization Hokkaido Cancer Center
Sapporo, Hokkaido, 003-0804, Japan
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National Hospital Organization Shikoku Cancer Center
Matsuyama, Ehime, 791-0280, Japan
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National Taiwan University Hospital
Taipei, 10002, Taiwan
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Nebraska Cancer Specialists
Omaha, Nebraska, 68130, United States
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Nemocnice Agel Ostrava-Vitkovice as
Ostrava-Vitkovice, 703 00, Czechia
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Niigata Cancer Center Hospital
Niigata, Niigata, 951-8566, Japan
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Northeast Georgia Medical Center
Gainesville, Georgia, 30501, United States
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Odense Universitetshospital
Odense C, 5000, Denmark
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Okayama University Hospital
Okayama, Okayama-ken, 700-8558, Japan
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Oncare
Mexico City, Mexico City, 03810, Mexico
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Oncoclinicas Rio de Janeiro S A
Rio de Janeiro, 22250-905, Brazil
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Oncology Associates of Oregon, PC
Eugene, Oregon, 97401, United States
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Oncology Hematology Associates
Springfield, Missouri, 65807, United States
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Oncology Hematology Care Incorporated
Cincinnati, Ohio, 45242, United States
-
Oregon Health and Science University
Portland, Oregon, 97239, United States
-
Orszagos Koranyi Pulmonologiai Intezet
Budapest, 1121, Hungary
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Osaka International Cancer Institute
Osaka, Osaka, 541-8567, Japan
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Ospedale Regionale di Bellinzona e Vali
Mendrisio, 6850, Switzerland
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Our Lady of the Lake Cancer Institute
Baton Rouge, Louisiana, 70808, United States
-
Prince of Wales Hospital, Chinese University of Hong Kong
Shatin, New Territories, Hong Kong
-
Princess Margaret Hospital
Kowloon, Hong Kong
-
Rabin Medical Center
Petah Tikva, 4941492, Israel
-
Rambam Medical Center
Haifa, 3109601, Israel
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Reformatus Pulmonologiai Centrum
Törökbálint, 2045, Hungary
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Regionshospitalet Godstrup
Herning, 7400, Denmark
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Rigshospitalet
Copenhagen, 2100, Denmark
-
Rutgers Cancer Institute of New Jersey
New Brunswick, New Jersey, 08901, United States
-
Saint Lukes Hospital SA
Thessaloniki, 55236, Greece
-
Saitama Medical University International Medical Center
Hidaka-shi, Saitama, 350-1298, Japan
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Sakarya Egitim ve Arastirma Hastanesi
Sakarya, 54290, Turkey (Türkiye)
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Samsung Medical Center
Seoul, 06351, South Korea
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Santa Casa de Misericordia de Passos
Passos, Minas Gerais, 37904-020, Brazil
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Sarah Cannon Research Institute
Nashville, Tennessee, 37203, United States
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Semmelweis Egyetem
Budapest, 1083, Hungary
-
Seoul National University Bundang Hospital
Seongnam-si, Gyeonggi-do, 13620, South Korea
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Seoul National University Hospital
Seoul, 03080, South Korea
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Severance Hospital Yonsei University Health System
Seoul, 03722, South Korea
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Shaare Zedek Medical Center
Jerusalem, 9103102, Israel
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Shanghai Chest Hospital
Shanghai, Shanghai Municipality, 200030, China
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Shanghai Pulmonary Hospital
Shanghai, Shanghai Municipality, 200433, China
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Shanxi Provincial Cancer Hospital
Taiyuan, Shanxi, 030009, China
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Shizuoka Cancer Center
Sunto-gun, Shizuoka, 411-8777, Japan
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Sir Charles Gairdner Hospital
Nedlands, Western Australia, 6009, Australia
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Sotiria General Hospital
Athens, 11527, Greece
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Spitalul Municipal Ploiesti
Ploieşti, 100337, Romania
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Sun Yat-sen University Cancer Center
Guangzhou, Guangdong, 510060, China
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Swedish Cancer Institute
Seattle, Washington, 98104, United States
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Taipei Veterans General Hospital
Taipei, 11217, Taiwan
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Texas Oncology - Dallas Fort Worth
Dallas, Texas, 75246, United States
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The Affiliated Cancer Hospital of Shandong First Medical University
Jinan, Shandong, 250117, China
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The Affiliated Hospital of Inner Mongolia Medical University
Hohhot, Inner Mongolia, 010010, China
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The Cancer Institute Hospital of Japanese Foundation for Cancer Research
Koto-ku, Tokyo, 135-8550, Japan
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The First Affiliated Hospital Of Ningbo University
Ningbo, Zhejiang, 315010, China
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The First Affiliated Hospital of Wenzhou Medical University
Wenzhou, Zhejiang, 325015, China
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The First Affiliated Hospital of Xian Jiaotong University
Xi’an, Shanxi, 710065, China
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The First Affiliated Hospital of Zhengzhou University
Zhengzhou, Henan, 450066, China
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The Medical College of Wisconsin
Milwaukee, Wisconsin, 53226, United States
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The Ohio State University
Columbus, Ohio, 43210, United States
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The Second Attached Hospital Of Fujian Medical University
Quanzhou, Fujian, 362002, China
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Tianjin Peoples Hospital
Tianjin, Tianjin Municipality, 300121, China
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US Oncology Research Investigational Products Center
Dallas, Texas, 75246, United States
-
Unidade Local de Saude de Matosinhos, EPE - Hospital Pedro Hispano
Matosinhos Municipality, 4464-513, Portugal
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Universitaetsklinikum Dresden
Dresden, 01307, Germany
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Universitaetsklinikum Essen
Essen, 45147, Germany
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Universitaetsklinikum Heidelberg
Heidelberg, 69126, Germany
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Universitaetsklinikum Krems
Krems, 3500, Austria
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Universitaetsklinikum Wuerzburg
Würzburg, 97078, Germany
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Universitaetsspital Basel
Basel, 4052, Switzerland
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Universitair Medisch Centrum Groningen
Groningen, 9713 GZ, Netherlands
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Universitair Ziekenhuis Antwerpen
Edegem, 2650, Belgium
-
Universitair Ziekenhuis Brussel
Brussels, 1090, Belgium
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Universite Catholique de Louvain Cliniques Universitaires Saint Luc
Brussels, 1200, Belgium
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University Cancer and Blood Center LLC
Athens, Georgia, 30607, United States
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University Hospital Muenster
Münster, 48149, Germany
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University Hospitals Cleveland Medical Center
Cleveland, Ohio, 44106, United States
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University of Illinois Chicago
Chicago, Illinois, 60612, United States
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University of Pittsburgh Medical Center
Pittsburgh, Pennsylvania, 15232, United States
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University of Southern California
Los Angeles, California, 90033, United States
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University of Texas MD Anderson Cancer Center
Houston, Texas, 77030, United States
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Uniwersyteckie Centrum Kliniczne
Gdansk, 80-214, Poland
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VM Medical Park Mersin Hastanesi
Mersin, 33200, Turkey (Türkiye)
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Virginia Commonwealth University Massey Cancer Center
Richmond, Virginia, 23298, United States
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Virginia Oncology Associates
Newport News, Virginia, 23606, United States
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Vseobecna fakultni nemocnice v Praze
Prague, 128 08, Czechia
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Wakayama Medical University Hospital
Wakayama, Wakayama, 641-8510, Japan
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Wake Forest University Health Sciences
Winston-Salem, North Carolina, 27157, United States
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West China Hospital of Sichuan University
Chengdu, Sichuan, 611135, China
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Wielkopolskie Centrum Pulmonologii i Torakochirurgii imienia Eugenii i Janusza Zeylandow
Poznan, 60-569, Poland
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Wollongong Hospital
Wollongong, New South Wales, 2500, Australia
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Xinqiao Hospital
Chongqing, Chongqing Municipality, 400037, China
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Xuzhou Central Hospital
Xuzhou, Jiangsu, 221009, China
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Yale New Haven Hospital
New Haven, Connecticut, 06510, United States
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Ziekenhuis Oost-Limburg
Genk, 3600, Belgium
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the First Affiliated Hospital Zhejiang University School of Medicine
Hangzhou, Zhejiang, 310003, China
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