New targeted therapy shows promise for concussion sufferers

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: Participants must meet ALL of the following inclusion criteria: * 18-49 years of age * Normal/corrected vision * Diagnosed with complex mTBI in the past 8 days-6 months with clear mechanism of injury * Glascow coma scale (GCS) score no less than 13 * Reported or sign of mTBI including loss of consciousness, amnesia, disorientation/confusion, dizziness, imbalance, memory problems, vomiting * Complex mTBI-related symptoms and/or impairments in at least one of the following areas: anxiety/mood, cognitive, migraine, ocular, vestibular, sleep, autonomic; per a comprehensive assessment, clinical exam/interview, and adjudication process. Exclusion Criteria: Participants will be excluded if they meet one or more of the following exclusion criteria: * History of vestibular disorder (e.g., benign paroxysmal positional vertigo, unilateral, or bilateral vestibular hypofunction) * History of neurological disorder * Previous moderate to severe TBI * History of brain surgery, malformations or tumors * Diagnosed with cardiac, peripheral or cerebrovascular disease * Experienced chest pain or shortness of breath while at rest or with mild exertion * Been told by a doctor to only conduct physical activity under medical supervision * Previous moderate to severe TBI * \< 8 days or \>6 months following current complex mTBI * Currently pregnant or become pregnant during study * Currently involved in litigation associated with current or previous mTBI * Currently on workman's compensation * Previously participated in the study * Previously received treatment at either site within last two years as this will unblind treatment group(s) * Members of same household will not be included as they may determine their group assignment if more than one person from same household is included and assigned to different groups. * Please note that participants with a history of mTBI, ADHD/LD, migraine, or motion sickness will NOT be excluded. We will adjust for any imbalance in the groups on these factors via covariate analysis.