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Which nerve block eases C-Section pain best? new trial aims to find out

NCT ID NCT07292662

Symptom relief Sponsor: University of Padova Source: ClinicalTrials.gov ↗

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now This study
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study compares two ultrasound-guided pain relief injections—TAP block and ESP block—for women having a planned cesarean section. Both use the same local anesthetic (ropivacaine) to numb nerves, but they target different areas. The main goal is to see which provides better pain control at rest six hours after surgery. Researchers will also track pain at later times, opioid use, and how quickly women can walk and start breastfeeding.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
ropivacaine
What this could lead to
If one block proves better, it could improve pain control and reduce opioid use after cesarean delivery.
What could go wrong
This is a small, early-stage study (90 participants) comparing two established techniques, so differences may be small or not clinically meaningful.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 90 people

The number the study aims to enrol. It can still change while the study runs.

Started

Jan 2026

Expected to finish

Oct 2027

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

18 to 45 years

Sex

Female participants only

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Age between 18 and 45 years * Elective cesarean section * Ability to provide informed consent Exclusion Criteria: * Allergy to any of the drugs used in the study * Heart disease with impaired cardiac function * Stage III or higher kidney failure * Coagulation disorders (platelets \<100,000/μL or INR \>1.5) or severe liver disease * Degenerative central nervous system diseases or peripheral neuropathies * Previous uterine surgery (e.g., myomectomy) * Previous cesarean section Pre-pregnancy weight \<55 kg

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Cesarean delivery Regional anesthesia block

How to take part

Only the study team decides who joins. These are the ways to reach them.

  1. The places running it

    1 site. The list below names each one and where it is.

  2. The official record

    ClinicalTrials.gov lists the study team's own contact details, including names and phone numbers. We don't republish those.

    Open the record ↗

  3. A doctor treating you

    A doctor who knows your case can contact a study site on your behalf, and can tell you whether this study is worth pursuing at all.

Contacts and locations

Locations

  • University Hospital of Padua

    RECRUITING

    Padova, 35127, Italy

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