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New combo aims to shrink prostate cancer before surgery

NCT ID NCT05873192

First seen Jan 04, 2026 · Last updated Apr 28, 2026 · Updated 21 times

Summary

This study tests whether adding the drug talazoparib to standard hormone therapy and enzalutamide can help shrink prostate cancer that has spread to lymph nodes. About 30 men will receive the combination before having their prostate removed. The goal is to see if the treatment is safe and effective enough to control the disease before surgery.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • M D Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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