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Can tai chi ease gulf war Veterans' pain and fatigue?

NCT ID NCT02661997

What the study statuses mean

This study's is highlighted.

Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed This study
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looked at whether Tai Chi or a wellness program could help Gulf War Veterans with chronic pain, fatigue, and mood problems. 114 Veterans took part, with sessions done in person or later by video due to COVID-19. The goal was to see if these gentle mind-body approaches reduce symptoms and improve daily life.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Tai Chi (a gentle exercise combining movement, meditation, and breathing)
What this could lead to
If it works, this could offer a safe, drug-free way to ease pain and fatigue for Gulf War Veterans.
What could go wrong
This is a small, completed study that was disrupted by COVID-19 and switched to remote delivery, which may affect results. It does not test a cure, only symptom relief.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

114 people

The number who actually took part.

Started

Jun 2017

Finished

Sep 2025

Lead sponsor

A government agency

The lead sponsor is a US federal agency other than the NIH.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

Children (under 18), adults (18 to 64) and older adults (65 and over)

Sex

Anyone

Healthy volunteers

Not accepted

This study is not open to healthy volunteers. The entry requirements below say who it is open to.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Served in the 1991 Gulf War. * Meets criteria for chronic multisymptom illness (CMI) based on CDC criteria32 characterized by one or more symptoms of at least 6 months duration from at least two of three symptom categories: 1) musculoskeletal pain (muscle pain, joint pain, or stiffness); 2) fatigue; and 3) mood-cognition. * One symptom of CMI must be musculoskeletal or joint pain or stiffness of at least 6 months duration (in addition to fatigue or cognitive complaints of the CDC criteria32). * Not planning to relocate in next 3 months * English-Speaking: English is the only language to be used during the exercise training program. Our self-reported outcome measures are obtained from validated English-version questionnaires. In addition, using other languages would likely require separate classes, recruitment and instructors which are beyond our current study scope. * Has access to a home computer or device that will allow telehealth delivery of the intervention. Exclusion Criteria: * Lacks the capacity to provide consent * Major medical, psychiatric, or neurological disorder or has a moderate or severe traumatic brain injury, which could interfere with their ability to safely engage in Tai Chi exercises. * Change in psychotropic or pain medication during the past month * This will minimize amount of symptom change due to medication alterations * Once enrolled, medication changes are nonetheless expected and will be monitored * Regular current Tai Chi, mindfulness, or yoga practice, defined as at least three hours per week for more than three months. * Veterans with prior experience who do not currently engage in regular practice at this level will be eligible * Reports difficulty standing on feet for the majority of a Tai Chi class (approximately 60 minutes). * Participants who are disruptive or disrespectful or engage in behavior that threatens staff and/or participant safety may be terminated from the study. * Participants who are currently involved in another treatment study that might confound our findings (e.g., treatments for GWI, pain).

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • VA Boston Healthcare System Jamaica Plain Campus, Jamaica Plain, MA

    Boston, Massachusetts, 02130-4817, United States