Why is gout so common in polynesians? scientists look to genes for answers
NCT ID NCT04900090
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study looked at 33 Polynesian adults with and without gout to find genetic clues about why the disease is so common in this group. Researchers compared family members with gout to those without, using genetic tests and CT scans to measure uric acid crystal deposits. The goal was to better understand how genes and environment together lead to gout, not to test a new treatment.
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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33 people
The number who actually took part.
- Started
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May 2021
- Finished
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Aug 2021
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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18 to 80 years
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria : Case group : * Gout patients * Polynesian origin * Aged 18 to 80 years * Agreeing to participate in the study * Having a 1st or 2nd degree relative who is also gouty and a 1st degree relative of the same generation and sex who is not gouty Control group : * Non-gouty individuals who are 1st degree relatives of a gouty patient of the same generation and sex * Aged 18 to 80 years * Agreeing to participate in the study Exclusion Criteria : * Pregnant women * Persons under guardianship, curatorship or other legal incapacity * Persons with a contraindication to Magnetic resonance imaging (MRI) examination * For non-gouty controls : current hyperuricemic treatment (Allopurinol, Febuxostat, Probenecid or Benzbromarone) * For gouty case : not participating in the TOPATA study (NCT04812886)
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Centre Hospitalier de Polynésie Française
Papeete, Ville de Pirae, 98713, French Polynesia
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Other studies related to the condition(s) this trial covers.
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