Skin deep: new study probes hidden signals in hidradenitis
NCT ID NCT07278011
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study examined skin samples from 15 people with hidradenitis suppurativa (HS) and 15 healthy volunteers to measure certain genes and proteins linked to inflammation. The goal was to better understand what causes HS and find possible markers of disease severity. No treatment was given; it was purely an observational study to gather knowledge.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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30 people
The number who actually took part.
- Started
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Jan 2025
- Finished
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Nov 2025
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
The study population consists of adult patients aged 18 years and older with a clinical and/or histopathological diagnosis of hidradenitis suppurativa, as well as healthy control individuals aged 18 years and older without autoimmune or inflammatory disease. Healthy controls were selected to be similar to the hidradenitis suppurativa group in terms of age, sex, and metabolic characteristics. Control participants were recruited among individuals presenting for benign nevus excision at the Trakya University Medical Faculty Department of Dermatology.
- Ages
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18 years and older
- Sex
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Anyone
- Healthy volunteers
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Accepted
You do not need to have the condition being studied to take part.
Show the full entry requirements Hide the full entry requirements
Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Age ≥ 18 years. Ability to read and write. For the patient group: clinical and/or histopathological diagnosis of hidradenitis suppurativa for at least 6 months. No use of topical treatments within the last 2 weeks, conventional systemic treatments within the last 1 month, or biologic therapies within the last 3 months prior to enrollment. Not pregnant at the time of enrollment. Absence of known immunosuppression or malignancy. For the control group: healthy individuals aged ≥18 years without any autoimmune or inflammatory disease, matched to the hidradenitis suppurativa group in terms of age, sex, and metabolic characteristics, who presented for benign nevus excision at the Trakya University Medical Faculty Department of Dermatology. Exclusion Criteria: * Presence of any autoimmune or inflammatory disease other than hidradenitis suppurativa. Current pregnancy. Known immunosuppression. History of malignancy. Use of topical, systemic conventional, or biologic treatments outside the defined washout periods.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Trakya University Medical Faculty, Department of Dermatology
Edirne, 22030, Turkey (Türkiye)
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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